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Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid.
Drieu A, Du S, Storck SE, Rustenhoven J, Papadopoulos Z, Dykstra T, Zhong F, Kim K, Blackburn S, Mamuladze T, Harari O, Karch CM, Bateman RJ, Perrin R, Farlow M, Chhatwal J; Dominantly Inherited Alzheimer Network; Hu S, Randolph GJ, Smirnov I, Kipnis J. Drieu A, et al. Among authors: storck se. Nature. 2022 Nov;611(7936):585-593. doi: 10.1038/s41586-022-05397-3. Epub 2022 Nov 9. Nature. 2022. PMID: 36352225 Free PMC article.
Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.
Storck SE, Meister S, Nahrath J, Meißner JN, Schubert N, Di Spiezio A, Baches S, Vandenbroucke RE, Bouter Y, Prikulis I, Korth C, Weggen S, Heimann A, Schwaninger M, Bayer TA, Pietrzik CU. Storck SE, et al. J Clin Invest. 2016 Jan;126(1):123-36. doi: 10.1172/JCI81108. Epub 2015 Nov 30. J Clin Invest. 2016. PMID: 26619118 Free PMC article.
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.
Marques ARA, Di Spiezio A, Thießen N, Schmidt L, Grötzinger J, Lüllmann-Rauch R, Damme M, Storck SE, Pietrzik CU, Fogh J, Bär J, Mikhaylova M, Glatzel M, Bassal M, Bartsch U, Saftig P. Marques ARA, et al. Among authors: storck se. Autophagy. 2020 May;16(5):811-825. doi: 10.1080/15548627.2019.1637200. Epub 2019 Jul 16. Autophagy. 2020. PMID: 31282275 Free PMC article.
The LepR-mediated leptin transport across brain barriers controls food reward.
Di Spiezio A, Sandin ES, Dore R, Müller-Fielitz H, Storck SE, Bernau M, Mier W, Oster H, Jöhren O, Pietrzik CU, Lehnert H, Schwaninger M. Di Spiezio A, et al. Among authors: storck se. Mol Metab. 2018 Feb;8:13-22. doi: 10.1016/j.molmet.2017.12.001. Epub 2017 Dec 7. Mol Metab. 2018. PMID: 29254602 Free PMC article.
Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease.
Marengo L, Armbrust F, Schoenherr C, Storck SE, Schmitt U, Zampar S, Wirths O, Altmeppen H, Glatzel M, Kaether C, Weggen S, Becker-Pauly C, Pietrzik CU. Marengo L, et al. Among authors: storck se. Cell Mol Life Sci. 2022 Mar 2;79(3):168. doi: 10.1007/s00018-022-04205-5. Cell Mol Life Sci. 2022. PMID: 35235058 Free PMC article.
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