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Page 1
Plasminogen activation triggers transthyretin amyloidogenesis in vitro.
Mangione PP, Verona G, Corazza A, Marcoux J, Canetti D, Giorgetti S, Raimondi S, Stoppini M, Esposito M, Relini A, Canale C, Valli M, Marchese L, Faravelli G, Obici L, Hawkins PN, Taylor GW, Gillmore JD, Pepys MB, Bellotti V. Mangione PP, et al. Among authors: stoppini m. J Biol Chem. 2018 Sep 14;293(37):14192-14199. doi: 10.1074/jbc.RA118.003990. Epub 2018 Jul 17. J Biol Chem. 2018. PMID: 30018138 Free PMC article.
Properties of some variants of human beta2-microglobulin and amyloidogenesis.
Corazza A, Pettirossi F, Viglino P, Verdone G, Garcia J, Dumy P, Giorgetti S, Mangione P, Raimondi S, Stoppini M, Bellotti V, Esposito G. Corazza A, et al. Among authors: stoppini m. J Biol Chem. 2004 Mar 5;279(10):9176-89. doi: 10.1074/jbc.M310779200. Epub 2003 Dec 4. J Biol Chem. 2004. PMID: 14660575 Free article.
Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis.
Relini A, Canale C, De Stefano S, Rolandi R, Giorgetti S, Stoppini M, Rossi A, Fogolari F, Corazza A, Esposito G, Gliozzi A, Bellotti V. Relini A, et al. Among authors: stoppini m. J Biol Chem. 2006 Jun 16;281(24):16521-9. doi: 10.1074/jbc.M513827200. Epub 2006 Apr 6. J Biol Chem. 2006. PMID: 16601119 Free article.
Proteomics in protein misfolding diseases.
Stoppini M, Obici L, Lavatelli F, Giorgetti S, Marchese L, Moratti R, Bellotti V, Merlini G. Stoppini M, et al. Clin Chem Lab Med. 2009;47(6):627-35. doi: 10.1515/CCLM.2009.164. Clin Chem Lab Med. 2009. PMID: 19527136 Review.
Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils.
Giorgetti S, Raimondi S, Pagano K, Relini A, Bucciantini M, Corazza A, Fogolari F, Codutti L, Salmona M, Mangione P, Colombo L, De Luigi A, Porcari R, Gliozzi A, Stefani M, Esposito G, Bellotti V, Stoppini M. Giorgetti S, et al. Among authors: stoppini m. J Biol Chem. 2011 Jan 21;286(3):2121-31. doi: 10.1074/jbc.M110.178376. Epub 2010 Nov 10. J Biol Chem. 2011. PMID: 21068391 Free PMC article.
Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin.
Mangione PP, Esposito G, Relini A, Raimondi S, Porcari R, Giorgetti S, Corazza A, Fogolari F, Penco A, Goto Y, Lee YH, Yagi H, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Chiti F, Rolandi R, Taylor GW, Pepys MB, Stoppini M, Bellotti V. Mangione PP, et al. Among authors: stoppini m. J Biol Chem. 2013 Oct 25;288(43):30917-30. doi: 10.1074/jbc.M113.498857. Epub 2013 Sep 6. J Biol Chem. 2013. PMID: 24014031 Free PMC article.
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Mangione PP, Porcari R, Gillmore JD, Pucci P, Monti M, Porcari M, Giorgetti S, Marchese L, Raimondi S, Serpell LC, Chen W, Relini A, Marcoux J, Clatworthy IR, Taylor GW, Tennent GA, Robinson CV, Hawkins PN, Stoppini M, Wood SP, Pepys MB, Bellotti V. Mangione PP, et al. Among authors: stoppini m. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1539-44. doi: 10.1073/pnas.1317488111. Epub 2014 Jan 13. Proc Natl Acad Sci U S A. 2014. PMID: 24474780 Free PMC article.
Systemic amyloidosis: lessons from β2-microglobulin.
Stoppini M, Bellotti V. Stoppini M, et al. J Biol Chem. 2015 Apr 17;290(16):9951-8. doi: 10.1074/jbc.R115.639799. Epub 2015 Mar 6. J Biol Chem. 2015. PMID: 25750126 Free PMC article. Review.
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.
Marcoux J, Mangione PP, Porcari R, Degiacomi MT, Verona G, Taylor GW, Giorgetti S, Raimondi S, Sanglier-Cianférani S, Benesch JL, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Stoppini M, Robinson CV, Pepys MB, Bellotti V. Marcoux J, et al. Among authors: stoppini m. EMBO Mol Med. 2015 Oct;7(10):1337-49. doi: 10.15252/emmm.201505357. EMBO Mol Med. 2015. PMID: 26286619 Free PMC article.
84 results