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Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1.
Wattenberg MM, Coho H, Herrera VM, Graham K, Stone ML, Xue Y, Chang RB, Cassella C, Liu M, Choi-Bose S, Thomas SK, Choi H, Li Y, Markowitz K, Melendez L, Gianonne M, Bose N, Beatty GL. Wattenberg MM, et al. Among authors: stone ml. Sci Immunol. 2023 Nov 17;8(89):eadj5097. doi: 10.1126/sciimmunol.adj5097. Epub 2023 Nov 17. Sci Immunol. 2023. PMID: 37976347 Free PMC article.
Hepatocytes direct the formation of a pro-metastatic niche in the liver.
Lee JW, Stone ML, Porrett PM, Thomas SK, Komar CA, Li JH, Delman D, Graham K, Gladney WL, Hua X, Black TA, Chien AL, Majmundar KS, Thompson JC, Yee SS, O'Hara MH, Aggarwal C, Xin D, Shaked A, Gao M, Liu D, Borad MJ, Ramanathan RK, Carpenter EL, Ji A, de Beer MC, de Beer FC, Webb NR, Beatty GL. Lee JW, et al. Among authors: stone ml. Nature. 2019 Mar;567(7747):249-252. doi: 10.1038/s41586-019-1004-y. Epub 2019 Mar 6. Nature. 2019. PMID: 30842658 Free PMC article.
Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice.
Thomas SK, Wattenberg MM, Choi-Bose S, Uhlik M, Harrison B, Coho H, Cassella CR, Stone ML, Patel D, Markowitz K, Delman D, Chisamore M, Drees J, Bose N, Beatty GL. Thomas SK, et al. Among authors: stone ml. Nat Commun. 2023 Oct 10;14(1):6330. doi: 10.1038/s41467-023-41771-z. Nat Commun. 2023. PMID: 37816712 Free PMC article.
Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer.
Li Y, Chang RB, Stone ML, Delman D, Markowitz K, Xue Y, Coho H, Herrera VM, Li JH, Zhang L, Choi-Bose S, Giannone M, Shin SM, Coyne EM, Hernandez A, Gross NE, Charmsaz S, Ho WJ, Lee JW, Beatty GL. Li Y, et al. Among authors: stone ml. Cell Rep Med. 2024 Feb 20;5(2):101397. doi: 10.1016/j.xcrm.2024.101397. Epub 2024 Feb 1. Cell Rep Med. 2024. PMID: 38307029 Free PMC article.
Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins.
Stone ML, Lee J, Lee JW, Coho H, Tariveranmoshabad M, Wattenberg MM, Choi H, Herrera VM, Xue Y, Choi-Bose S, Zingone SK, Patel D, Markowitz K, Delman D, Balachandran VP, Beatty GL. Stone ML, et al. Nat Immunol. 2024 May;25(5):755-763. doi: 10.1038/s41590-024-01820-1. Epub 2024 Apr 19. Nat Immunol. 2024. PMID: 38641718
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
Stone ML, Chiappinelli KB, Li H, Murphy LM, Travers ME, Topper MJ, Mathios D, Lim M, Shih IM, Wang TL, Hung CF, Bhargava V, Wiehagen KR, Cowley GS, Bachman KE, Strick R, Strissel PL, Baylin SB, Zahnow CA. Stone ML, et al. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10981-E10990. doi: 10.1073/pnas.1712514114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203668 Free PMC article.
Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer.
Topper MJ, Vaz M, Chiappinelli KB, DeStefano Shields CE, Niknafs N, Yen RC, Wenzel A, Hicks J, Ballew M, Stone M, Tran PT, Zahnow CA, Hellmann MD, Anagnostou V, Strissel PL, Strick R, Velculescu VE, Baylin SB. Topper MJ, et al. Cell. 2017 Nov 30;171(6):1284-1300.e21. doi: 10.1016/j.cell.2017.10.022. Cell. 2017. PMID: 29195073 Free PMC article.
240 results