Stokes JM - Search Results

1

A brief guide to machine learning for antibiotic discovery.

Liu G, Stokes JM. Liu G, et al. Among authors: stokes jm. Curr Opin Microbiol. 2022 Oct;69:102190. doi: 10.1016/j.mib.2022.102190. Epub 2022 Aug 10. Curr Opin Microbiol. 2022. PMID: 35963098 Review.

2

A cell-based approach to characterize antimicrobial compounds through kinetic dose response.

MacNair CR, Stokes JM, French S, Myers CL, Iyer KR, Brown ED. MacNair CR, et al. Among authors: stokes jm. Bioorg Med Chem. 2016 Dec 15;24(24):6315-6319. doi: 10.1016/j.bmc.2016.09.053. Epub 2016 Sep 22. Bioorg Med Chem. 2016. PMID: 27713016

3

Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance.

Stokes JM, MacNair CR, Ilyas B, French S, Côté JP, Bouwman C, Farha MA, Sieron AO, Whitfield C, Coombes BK, Brown ED. Stokes JM, et al. Nat Microbiol. 2017 Mar 6;2:17028. doi: 10.1038/nmicrobiol.2017.28. Nat Microbiol. 2017. PMID: 28263303 Free PMC article.

4

A Deep Learning Approach to Antibiotic Discovery.

Stokes JM, Yang K, Swanson K, Jin W, Cubillos-Ruiz A, Donghia NM, MacNair CR, French S, Carfrae LA, Bloom-Ackermann Z, Tran VM, Chiappino-Pepe A, Badran AH, Andrews IW, Chory EJ, Church GM, Brown ED, Jaakkola TS, Barzilay R, Collins JJ. Stokes JM, et al. Cell. 2020 Feb 20;180(4):688-702.e13. doi: 10.1016/j.cell.2020.01.021. Cell. 2020. PMID: 32084340 Free PMC article.

5

Antibiotic discovery in the artificial intelligence era.

Lluka T, Stokes JM. Lluka T, et al. Among authors: stokes jm. Ann N Y Acad Sci. 2023 Jan;1519(1):74-93. doi: 10.1111/nyas.14930. Epub 2022 Nov 29. Ann N Y Acad Sci. 2023. PMID: 36447334 Review.

6

Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii.

Liu G, Catacutan DB, Rathod K, Swanson K, Jin W, Mohammed JC, Chiappino-Pepe A, Syed SA, Fragis M, Rachwalski K, Magolan J, Surette MG, Coombes BK, Jaakkola T, Barzilay R, Collins JJ, Stokes JM. Liu G, et al. Among authors: stokes jm. Nat Chem Biol. 2023 Nov;19(11):1342-1350. doi: 10.1038/s41589-023-01349-8. Epub 2023 May 25. Nat Chem Biol. 2023. PMID: 37231267

7

Applications of machine learning in microbial natural product drug discovery.

Arnold A, Alexander J, Liu G, Stokes JM. Arnold A, et al. Among authors: stokes jm. Expert Opin Drug Discov. 2023 Jul-Dec;18(11):1259-1272. doi: 10.1080/17460441.2023.2251400. Epub 2023 Aug 31. Expert Opin Drug Discov. 2023. PMID: 37651150 Review.

8

Chemical inhibition of bacterial ribosome biogenesis shows efficacy in a worm infection model.

Stokes JM, Selin C, Cardona ST, Brown ED. Stokes JM, et al. Antimicrob Agents Chemother. 2015 May;59(5):2918-20. doi: 10.1128/AAC.04690-14. Epub 2015 Feb 23. Antimicrob Agents Chemother. 2015. PMID: 25712357 Free PMC article.

9

Cold Stress Makes Escherichia coli Susceptible to Glycopeptide Antibiotics by Altering Outer Membrane Integrity.

Stokes JM, French S, Ovchinnikova OG, Bouwman C, Whitfield C, Brown ED. Stokes JM, et al. Cell Chem Biol. 2016 Feb 18;23(2):267-277. doi: 10.1016/j.chembiol.2015.12.011. Epub 2016 Feb 4. Cell Chem Biol. 2016. PMID: 26853624 Free article.

10

Bicarbonate Alters Bacterial Susceptibility to Antibiotics by Targeting the Proton Motive Force.

Farha MA, French S, Stokes JM, Brown ED. Farha MA, et al. Among authors: stokes jm. ACS Infect Dis. 2018 Mar 9;4(3):382-390. doi: 10.1021/acsinfecdis.7b00194. Epub 2018 Jan 4. ACS Infect Dis. 2018. PMID: 29264917

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