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VHH characterization. Comparison of recombinant with chemically synthesized anti-HER2 VHH.
Hartmann L, Botzanowski T, Galibert M, Jullian M, Chabrol E, Zeder-Lutz G, Kugler V, Stojko J, Strub JM, Ferry G, Frankiewicz L, Puget K, Wagner R, Cianférani S, Boutin JA. Hartmann L, et al. Among authors: stojko j. Protein Sci. 2019 Oct;28(10):1865-1879. doi: 10.1002/pro.3712. Epub 2019 Aug 29. Protein Sci. 2019. PMID: 31423659 Free PMC article.
S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization.
Boutin JA, Bouillaud F, Janda E, Gacsalyi I, Guillaumet G, Hirsch EC, Kane DA, Nepveu F, Reybier K, Dupuis P, Bertrand M, Chhour M, Le Diguarher T, Antoine M, Brebner K, Da Costa H, Ducrot P, Giganti A, Goswami V, Guedouari H, Michel PP, Patel A, Paysant J, Stojko J, Viaud-Massuard MC, Ferry G. Boutin JA, et al. Among authors: stojko j. Mol Pharmacol. 2019 Mar;95(3):269-285. doi: 10.1124/mol.118.114231. Epub 2018 Dec 19. Mol Pharmacol. 2019. PMID: 30567956 Free article.
Soaking suggests "alternative facts": Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-of-inhibition.
Ehrmann FR, Stojko J, Metz A, Debaene F, Barandun LJ, Heine A, Diederich F, Cianférani S, Reuter K, Klebe G. Ehrmann FR, et al. Among authors: stojko j. PLoS One. 2017 Apr 18;12(4):e0175723. doi: 10.1371/journal.pone.0175723. eCollection 2017. PLoS One. 2017. PMID: 28419165 Free PMC article.
TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.
Thébault S, Agez M, Chi X, Stojko J, Cura V, Telerman SB, Maillet L, Gautier F, Billas-Massobrio I, Birck C, Troffer-Charlier N, Karafin T, Honoré J, Senff-Ribeiro A, Montessuit S, Johnson CM, Juin P, Cianférani S, Martinou JC, Andrews DW, Amson R, Telerman A, Cavarelli J. Thébault S, et al. Among authors: stojko j. Sci Rep. 2016 Jan 27;6:19725. doi: 10.1038/srep19725. Sci Rep. 2016. PMID: 26813996 Free PMC article.
56 results