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Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF-1α.
Pelletier A, Nelius E, Fan Z, Khatchatourova E, Alvarado-Diaz A, He J, Krzywinska E, Sobecki M, Nagarajan S, Kerdiles Y, Fandrey J, Gotthardt D, Sexl V, de Bock K, Stockmann C. Pelletier A, et al. Among authors: stockmann c. EMBO Rep. 2023 Jun 5;24(6):e56156. doi: 10.15252/embr.202256156. Epub 2023 Mar 29. EMBO Rep. 2023. PMID: 36987917 Free PMC article.
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
Krzywinska E, Kantari-Mimoun C, Kerdiles Y, Sobecki M, Isagawa T, Gotthardt D, Castells M, Haubold J, Millien C, Viel T, Tavitian B, Takeda N, Fandrey J, Vivier E, Sexl V, Stockmann C. Krzywinska E, et al. Among authors: stockmann c. Nat Commun. 2017 Nov 17;8(1):1597. doi: 10.1038/s41467-017-01599-w. Nat Commun. 2017. PMID: 29150606 Free PMC article.
Hypoxia, Metabolism and Immune Cell Function.
Krzywinska E, Stockmann C. Krzywinska E, et al. Among authors: stockmann c. Biomedicines. 2018 May 15;6(2):56. doi: 10.3390/biomedicines6020056. Biomedicines. 2018. PMID: 29762526 Free PMC article. Review.
The transcription factor HIF-1α mediates plasticity of NKp46+ innate lymphoid cells in the gut.
Krzywinska E, Sobecki M, Nagarajan S, Zacharjasz J, Tambuwala MM, Pelletier A, Cummins E, Gotthardt D, Fandrey J, Kerdiles YM, Peyssonnaux C, Taylor CT, Sexl V, Stockmann C. Krzywinska E, et al. Among authors: stockmann c. J Exp Med. 2022 Feb 7;219(2):e20210909. doi: 10.1084/jem.20210909. Epub 2022 Jan 13. J Exp Med. 2022. PMID: 35024767 Free PMC article.
The Metabolic Basis of ILC Plasticity.
Pelletier A, Stockmann C. Pelletier A, et al. Among authors: stockmann c. Front Immunol. 2022 Apr 29;13:858051. doi: 10.3389/fimmu.2022.858051. eCollection 2022. Front Immunol. 2022. PMID: 35572512 Free PMC article. Review.
170 results