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Hydrogen peroxide signaling via its transformation to a stereospecific alkyl hydroperoxide that escapes reductive inactivation.
Queiroz RF, Stanley CP, Wolhuter K, Kong SMY, Rajivan R, McKinnon N, Nguyen GTH, Roveri A, Guttzeit S, Eaton P, Donald WA, Ursini F, Winterbourn CC, Ayer A, Stocker R. Queiroz RF, et al. Among authors: stocker r. Nat Commun. 2021 Nov 16;12(1):6626. doi: 10.1038/s41467-021-26991-5. Nat Commun. 2021. PMID: 34785665 Free PMC article.
Kynurenine is an endothelium-derived relaxing factor produced during inflammation.
Wang Y, Liu H, McKenzie G, Witting PK, Stasch JP, Hahn M, Changsirivathanathamrong D, Wu BJ, Ball HJ, Thomas SR, Kapoor V, Celermajer DS, Mellor AL, Keaney JF Jr, Hunt NH, Stocker R. Wang Y, et al. Among authors: stocker r. Nat Med. 2010 Mar;16(3):279-85. doi: 10.1038/nm.2092. Epub 2010 Feb 28. Nat Med. 2010. PMID: 20190767 Free PMC article.
Heme oxygenase-1 deficiency alters erythroblastic island formation, steady-state erythropoiesis and red blood cell lifespan in mice.
Fraser ST, Midwinter RG, Coupland LA, Kong S, Berger BS, Yeo JH, Andrade OC, Cromer D, Suarna C, Lam M, Maghzal GJ, Chong BH, Parish CR, Stocker R. Fraser ST, et al. Among authors: stocker r. Haematologica. 2015 May;100(5):601-10. doi: 10.3324/haematol.2014.116368. Epub 2015 Feb 14. Haematologica. 2015. PMID: 25682599 Free PMC article.
Therapeutic targeting of oxidative stress with coenzyme Q10 counteracts exaggerated diabetic cardiomyopathy in a mouse model of diabetes with diminished PI3K(p110α) signaling.
De Blasio MJ, Huynh K, Qin C, Rosli S, Kiriazis H, Ayer A, Cemerlang N, Stocker R, Du XJ, McMullen JR, Ritchie RH. De Blasio MJ, et al. Among authors: stocker r. Free Radic Biol Med. 2015 Oct;87:137-47. doi: 10.1016/j.freeradbiomed.2015.04.028. Epub 2015 Apr 30. Free Radic Biol Med. 2015. PMID: 25937176
Heme Oxygenases in Cardiovascular Health and Disease.
Ayer A, Zarjou A, Agarwal A, Stocker R. Ayer A, et al. Among authors: stocker r. Physiol Rev. 2016 Oct;96(4):1449-508. doi: 10.1152/physrev.00003.2016. Physiol Rev. 2016. PMID: 27604527 Free PMC article. Review.
739 results