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Interplay between metabolic identities in the intestinal crypt supports stem cell function.
Rodríguez-Colman MJ, Schewe M, Meerlo M, Stigter E, Gerrits J, Pras-Raves M, Sacchetti A, Hornsveld M, Oost KC, Snippert HJ, Verhoeven-Duif N, Fodde R, Burgering BM. Rodríguez-Colman MJ, et al. Among authors: stigter e. Nature. 2017 Mar 16;543(7645):424-427. doi: 10.1038/nature21673. Epub 2017 Mar 8. Nature. 2017. PMID: 28273069
A Single Complex Agpat2 Allele in a Patient With Partial Lipodystrophy.
Broekema MF, Massink MPG, De Ligt J, Stigter ECA, Monajemi H, De Ridder J, Burgering BMT, van Haaften GW, Kalkhoven E. Broekema MF, et al. Among authors: stigter eca. Front Physiol. 2018 Sep 26;9:1363. doi: 10.3389/fphys.2018.01363. eCollection 2018. Front Physiol. 2018. PMID: 30319454 Free PMC article.
Fatty Acid and Carnitine Metabolism Are Dysregulated in Systemic Sclerosis Patients.
Ottria A, Hoekstra AT, Zimmermann M, van der Kroef M, Vazirpanah N, Cossu M, Chouri E, Rossato M, Beretta L, Tieland RG, Wichers CGK, Stigter E, Gulersonmez C, Bonte-Mineur F, Berkers CR, Radstake TRDJ, Marut W. Ottria A, et al. Among authors: stigter e. Front Immunol. 2020 May 22;11:822. doi: 10.3389/fimmu.2020.00822. eCollection 2020. Front Immunol. 2020. PMID: 32528464 Free PMC article.
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening.
Driehuis E, van Hoeck A, Moore K, Kolders S, Francies HE, Gulersonmez MC, Stigter ECA, Burgering B, Geurts V, Gracanin A, Bounova G, Morsink FH, Vries R, Boj S, van Es J, Offerhaus GJA, Kranenburg O, Garnett MJ, Wessels L, Cuppen E, Brosens LAA, Clevers H. Driehuis E, et al. Among authors: stigter eca. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26580-26590. doi: 10.1073/pnas.1911273116. Epub 2019 Dec 9. Proc Natl Acad Sci U S A. 2019. PMID: 31818951 Free PMC article.
Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism.
Stout GJ, Stigter EC, Essers PB, Mulder KW, Kolkman A, Snijders DS, van den Broek NJ, Betist MC, Korswagen HC, Macinnes AW, Brenkman AB. Stout GJ, et al. Mol Syst Biol. 2013 Jul 2;9:679. doi: 10.1038/msb.2013.35. Mol Syst Biol. 2013. PMID: 23820781 Free PMC article.
Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids.
Roodhart JM, Daenen LG, Stigter EC, Prins HJ, Gerrits J, Houthuijzen JM, Gerritsen MG, Schipper HS, Backer MJ, van Amersfoort M, Vermaat JS, Moerer P, Ishihara K, Kalkhoven E, Beijnen JH, Derksen PW, Medema RH, Martens AC, Brenkman AB, Voest EE. Roodhart JM, et al. Among authors: stigter ec. Cancer Cell. 2011 Sep 13;20(3):370-83. doi: 10.1016/j.ccr.2011.08.010. Cancer Cell. 2011. PMID: 21907927 Free article.
33 results