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The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state.
Adhikary T, Wortmann A, Schumann T, Finkernagel F, Lieber S, Roth K, Toth PM, Diederich WE, Nist A, Stiewe T, Kleinesudeik L, Reinartz S, Müller-Brüsselbach S, Müller R. Adhikary T, et al. Among authors: stiewe t. Nucleic Acids Res. 2015 May 26;43(10):5033-51. doi: 10.1093/nar/gkv331. Epub 2015 Apr 30. Nucleic Acids Res. 2015. PMID: 25934804 Free PMC article.
CRISPR-Cas9-based target validation for p53-reactivating model compounds.
Wanzel M, Vischedyk JB, Gittler MP, Gremke N, Seiz JR, Hefter M, Noack M, Savai R, Mernberger M, Charles JP, Schneikert J, Bretz AC, Nist A, Stiewe T. Wanzel M, et al. Among authors: stiewe t. Nat Chem Biol. 2016 Jan;12(1):22-8. doi: 10.1038/nchembio.1965. Epub 2015 Nov 23. Nat Chem Biol. 2016. PMID: 26595461 Free PMC article.
The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization.
Finkernagel F, Reinartz S, Lieber S, Adhikary T, Wortmann A, Hoffmann N, Bieringer T, Nist A, Stiewe T, Jansen JM, Wagner U, Müller-Brüsselbach S, Müller R. Finkernagel F, et al. Among authors: stiewe t. Oncotarget. 2016 Nov 15;7(46):75339-75352. doi: 10.18632/oncotarget.12180. Oncotarget. 2016. PMID: 27659538 Free PMC article.
149 results