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Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model.
Aparicio-Vergara M, Hommelberg PP, Schreurs M, Gruben N, Stienstra R, Shiri-Sverdlov R, Kloosterhuis NJ, de Bruin A, van de Sluis B, Koonen DP, Hofker MH. Aparicio-Vergara M, et al. Among authors: stienstra r. Hepatology. 2013 Feb;57(2):566-76. doi: 10.1002/hep.26046. Epub 2013 Jan 10. Hepatology. 2013. PMID: 22941955
Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.
Hendrikx T, Bieghs V, Walenbergh SM, van Gorp PJ, Verheyen F, Jeurissen ML, Steinbusch MM, Vaes N, Binder CJ, Koek GH, Stienstra R, Netea MG, Hofker MH, Shiri-Sverdlov R. Hendrikx T, et al. Among authors: stienstra r. PLoS One. 2013 Dec 2;8(12):e78792. doi: 10.1371/journal.pone.0078792. eCollection 2013. PLoS One. 2013. PMID: 24312444 Free PMC article.
PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism.
van Diepen JA, Jansen PA, Ballak DB, Hijmans A, Hooiveld GJ, Rommelaere S, Galland F, Naquet P, Rutjes FP, Mensink RP, Schrauwen P, Tack CJ, Netea MG, Kersten S, Schalkwijk J, Stienstra R. van Diepen JA, et al. Among authors: stienstra r. J Hepatol. 2014 Aug;61(2):366-72. doi: 10.1016/j.jhep.2014.04.013. Epub 2014 Apr 18. J Hepatol. 2014. PMID: 24751833
Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids.
Janssen AWF, Houben T, Katiraei S, Dijk W, Boutens L, van der Bolt N, Wang Z, Brown JM, Hazen SL, Mandard S, Shiri-Sverdlov R, Kuipers F, Willems van Dijk K, Vervoort J, Stienstra R, Hooiveld GJEJ, Kersten S. Janssen AWF, et al. Among authors: stienstra r. J Lipid Res. 2017 Jul;58(7):1399-1416. doi: 10.1194/jlr.M075713. Epub 2017 May 22. J Lipid Res. 2017. PMID: 28533304 Free PMC article.
Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions.
Thiem K, Hoeke G, Zhou E, Hijmans A, Houben T, Boels MG, Mol IM, Lutgens E, Shiri-Sverdlov R, Bussink J, Kanneganti TD, Boon MR, Stienstra R, Tack CJ, Rensen PC, Netea MG, Berbée JF, van Diepen JA. Thiem K, et al. Among authors: stienstra r. Diab Vasc Dis Res. 2020 Jan-Feb;17(1):1479164119892140. doi: 10.1177/1479164119892140. Epub 2019 Dec 23. Diab Vasc Dis Res. 2020. PMID: 31868000 Free PMC article.
Natural killer T cells in adipose tissue prevent insulin resistance.
Schipper HS, Rakhshandehroo M, van de Graaf SF, Venken K, Koppen A, Stienstra R, Prop S, Meerding J, Hamers N, Besra G, Boon L, Nieuwenhuis EE, Elewaut D, Prakken B, Kersten S, Boes M, Kalkhoven E. Schipper HS, et al. Among authors: stienstra r. J Clin Invest. 2012 Sep;122(9):3343-54. doi: 10.1172/JCI62739. Epub 2012 Aug 6. J Clin Invest. 2012. PMID: 22863618 Free PMC article.
203 results