Stewart CF - Search Results

1

Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03).

Gajjar A, Robinson GW, Smith KS, Lin T, Merchant TE, Chintagumpala M, Mahajan A, Su J, Bouffet E, Bartels U, Schechter T, Hassall T, Robertson T, Nicholls W, Gururangan S, Schroeder K, Sullivan M, Wheeler G, Hansford JR, Kellie SJ, McCowage G, Cohn R, Fisher MJ, Krasin MJ, Stewart CF, Broniscer A, Buchhalter I, Tatevossian RG, Orr BA, Neale G, Klimo P Jr, Boop F, Srinivasan A, Pfister SM, Gilbertson RJ, Onar-Thomas A, Ellison DW, Northcott PA. Gajjar A, et al. Among authors: stewart cf. J Clin Oncol. 2021 Mar 1;39(7):822-835. doi: 10.1200/JCO.20.01372. Epub 2021 Jan 6. J Clin Oncol. 2021. PMID: 33405951 Free PMC article. Clinical Trial.

2

Clinical pharmacodynamics of continuous infusion topotecan in children: systemic exposure predicts hematologic toxicity.

Stewart CF, Baker SD, Heideman RL, Jones D, Crom WR, Pratt CB. Stewart CF, et al. J Clin Oncol. 1994 Sep;12(9):1946-54. doi: 10.1200/JCO.1994.12.9.1946. J Clin Oncol. 1994. PMID: 8083716 Clinical Trial.

3

Phase I study of topotecan for pediatric patients with malignant solid tumors.

Pratt CB, Stewart C, Santana VM, Bowman L, Furman W, Ochs J, Marina N, Kuttesch JF, Heideman R, Sandlund JT, et al. Pratt CB, et al. J Clin Oncol. 1994 Mar;12(3):539-43. doi: 10.1200/JCO.1994.12.3.539. J Clin Oncol. 1994. PMID: 8120551 Clinical Trial.

4

Cerebrospinal fluid pharmacokinetics and penetration of continuous infusion topotecan in children with central nervous system tumors.

Baker SD, Heideman RL, Crom WR, Kuttesch JF, Gajjar A, Stewart CF. Baker SD, et al. Among authors: stewart cf. Cancer Chemother Pharmacol. 1996;37(3):195-202. doi: 10.1007/BF00688317. Cancer Chemother Pharmacol. 1996. PMID: 8529278

5

Phenytoin alters the disposition of topotecan and N-desmethyl topotecan in a patient with medulloblastoma.

Zamboni WC, Gajjar AJ, Heideman RL, Beijnen JH, Rosing H, Houghton PJ, Stewart CF. Zamboni WC, et al. Among authors: stewart cf. Clin Cancer Res. 1998 Mar;4(3):783-9. Clin Cancer Res. 1998. PMID: 9533548

6

A four-hour topotecan infusion achieves cytotoxic exposure throughout the neuraxis in the nonhuman primate model: implications for treatment of children with metastatic medulloblastoma.

Zamboni WC, Gajjar AJ, Mandrell TD, Einhaus SL, Danks MK, Rogers WP, Heideman RL, Houghton PJ, Stewart CF. Zamboni WC, et al. Among authors: stewart cf. Clin Cancer Res. 1998 Oct;4(10):2537-44. Clin Cancer Res. 1998. PMID: 9796988

7

Direct translation of a protracted irinotecan schedule from a xenograft model to a phase I trial in children.

Furman WL, Stewart CF, Poquette CA, Pratt CB, Santana VM, Zamboni WC, Bowman LC, Ma MK, Hoffer FA, Meyer WH, Pappo AS, Walter AW, Houghton PJ. Furman WL, et al. Among authors: stewart cf. J Clin Oncol. 1999 Jun;17(6):1815-24. doi: 10.1200/JCO.1999.17.6.1815. J Clin Oncol. 1999. PMID: 10561220 Clinical Trial.

8

Phase I study of combination topotecan and carboplatin in pediatric solid tumors.

Athale UH, Stewart C, Kuttesch JF, Moghrabi A, Meyer W, Pratt C, Gajjar A, Heideman RL. Athale UH, et al. J Clin Oncol. 2002 Jan 1;20(1):88-95. doi: 10.1200/JCO.2002.20.1.88. J Clin Oncol. 2002. PMID: 11773158 Clinical Trial.

9

Altered irinotecan pharmacokinetics in pediatric high-grade glioma patients receiving enzyme-inducing anticonvulsant therapy.

Crews KR, Stewart CF, Jones-Wallace D, Thompson SJ, Houghton PJ, Heideman RL, Fouladi M, Bowers DC, Chintagumpala MM, Gajjar A. Crews KR, et al. Among authors: stewart cf. Clin Cancer Res. 2002 Jul;8(7):2202-9. Clin Cancer Res. 2002. PMID: 12114421 Clinical Trial.

10

A pilot study of protracted topotecan dosing using a pharmacokinetically guided dosing approach in children with solid tumors.

Santana VM, Zamboni WC, Kirstein MN, Tan M, Liu T, Gajjar A, Houghton PJ, Stewart CF. Santana VM, et al. Among authors: stewart cf. Clin Cancer Res. 2003 Feb;9(2):633-40. Clin Cancer Res. 2003. PMID: 12576429 Clinical Trial.

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