Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

48 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R).
Ferrisi R, Gado F, Polini B, Ricardi C, Mohamed KA, Stevenson LA, Ortore G, Rapposelli S, Saccomanni G, Pertwee RG, Laprairie RB, Manera C, Chiellini G. Ferrisi R, et al. Among authors: stevenson la. Front Chem. 2022 Sep 27;10:984069. doi: 10.3389/fchem.2022.984069. eCollection 2022. Front Chem. 2022. PMID: 36238097 Free PMC article.
Synthesis and structure-activity relationships of amide and hydrazide analogues of the cannabinoid CB(1) receptor antagonist N-(piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716).
Francisco ME, Seltzman HH, Gilliam AF, Mitchell RA, Rider SL, Pertwee RG, Stevenson LA, Thomas BF. Francisco ME, et al. Among authors: stevenson la. J Med Chem. 2002 Jun 20;45(13):2708-19. doi: 10.1021/jm010498v. J Med Chem. 2002. PMID: 12061874
Allosteric modulation of the cannabinoid CB1 receptor.
Price MR, Baillie GL, Thomas A, Stevenson LA, Easson M, Goodwin R, McLean A, McIntosh L, Goodwin G, Walker G, Westwood P, Marrs J, Thomson F, Cowley P, Christopoulos A, Pertwee RG, Ross RA. Price MR, et al. Among authors: stevenson la. Mol Pharmacol. 2005 Nov;68(5):1484-95. doi: 10.1124/mol.105.016162. Epub 2005 Aug 19. Mol Pharmacol. 2005. PMID: 16113085
Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe.
Laprairie RB, Kulkarni AR, Kulkarni PM, Hurst DP, Lynch D, Reggio PH, Janero DR, Pertwee RG, Stevenson LA, Kelly ME, Denovan-Wright EM, Thakur GA. Laprairie RB, et al. Among authors: stevenson la. ACS Chem Neurosci. 2016 Jun 15;7(6):776-98. doi: 10.1021/acschemneuro.6b00041. Epub 2016 Apr 25. ACS Chem Neurosci. 2016. PMID: 27046127 Free PMC article.
Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.
Laprairie RB, Kulkarni PM, Deschamps JR, Kelly MEM, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin TP, Denovan-Wright EM, Thakur GA. Laprairie RB, et al. Among authors: stevenson la. ACS Chem Neurosci. 2017 Jun 21;8(6):1188-1203. doi: 10.1021/acschemneuro.6b00310. Epub 2017 Feb 7. ACS Chem Neurosci. 2017. PMID: 28103441
Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief.
Gado F, Di Cesare Mannelli L, Lucarini E, Bertini S, Cappelli E, Digiacomo M, Stevenson LA, Macchia M, Tuccinardi T, Ghelardini C, Pertwee RG, Manera C. Gado F, et al. Among authors: stevenson la. J Med Chem. 2019 Jan 10;62(1):276-287. doi: 10.1021/acs.jmedchem.8b00368. Epub 2018 Jul 23. J Med Chem. 2019. PMID: 29990428
48 results