Stevenson AJ - Search Results

1

Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo.

Stevenson AJ, Ager EI, Proctor MA, Škalamera D, Heaton A, Brown D, Gabrielli BG. Stevenson AJ, et al. Sci Rep. 2018 Mar 23;8(1):5144. doi: 10.1038/s41598-018-22882-w. Sci Rep. 2018. PMID: 29572477 Free PMC article.

2

Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo.

Oo ZY, Stevenson AJ, Proctor M, Daignault SM, Walpole S, Lanagan C, Chen J, Škalamera D, Spoerri L, Ainger SA, Sturm RA, Haass NK, Gabrielli B. Oo ZY, et al. Among authors: stevenson aj. Clin Cancer Res. 2018 Jun 15;24(12):2901-2912. doi: 10.1158/1078-0432.CCR-17-2701. Epub 2018 Mar 13. Clin Cancer Res. 2018. PMID: 29535131

3

Inhibition of Aurora A and Aurora B Is Required for the Sensitivity of HPV-Driven Cervical Cancers to Aurora Kinase Inhibitors.

Martin D, Fallaha S, Proctor M, Stevenson A, Perrin L, McMillan N, Gabrielli B. Martin D, et al. Mol Cancer Ther. 2017 Sep;16(9):1934-1941. doi: 10.1158/1535-7163.MCT-17-0159. Epub 2017 May 18. Mol Cancer Ther. 2017. PMID: 28522591

4

Aurora A Is Critical for Survival in HPV-Transformed Cervical Cancer.

Gabrielli B, Bokhari F, Ranall MV, Oo ZY, Stevenson AJ, Wang W, Murrell M, Shaikh M, Fallaha S, Clarke D, Kelly M, Sedelies K, Christensen M, McKee S, Leggatt G, Leo P, Skalamera D, Soyer HP, Gonda TJ, McMillan NA. Gabrielli B, et al. Among authors: stevenson aj. Mol Cancer Ther. 2015 Dec;14(12):2753-61. doi: 10.1158/1535-7163.MCT-15-0506. Epub 2015 Oct 29. Mol Cancer Ther. 2015. PMID: 26516156

5

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine.

Oo ZY, Proctor M, Stevenson AJ, Nazareth D, Fernando M, Daignault SM, Lanagan C, Walpole S, Bonazzi V, Škalamera D, Snell C, Haass NK, Larsen JE, Gabrielli B. Oo ZY, et al. Among authors: stevenson aj. Mol Oncol. 2019 Jul;13(7):1503-1518. doi: 10.1002/1878-0261.12497. Epub 2019 Jun 14. Mol Oncol. 2019. PMID: 31044505 Free PMC article.

6

Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma.

Lee WJ, Škalamera D, Dahmer-Heath M, Shakhbazov K, Ranall MV, Fox C, Lambie D, Stevenson AJ, Yaswen P, Gonda TJ, Gabrielli B. Lee WJ, et al. Among authors: stevenson aj. SLAS Discov. 2017 Mar;22(3):298-308. doi: 10.1177/1087057116679592. Epub 2016 Nov 23. SLAS Discov. 2017. PMID: 27872202 Free article.

7

Dysregulated G2 phase checkpoint recovery pathway reduces DNA repair efficiency and increases chromosomal instability in a wide range of tumours.

Fernando M, Duijf PHG, Proctor M, Stevenson AJ, Ehmann A, Vora S, Skalamera D, Adams M, Gabrielli B. Fernando M, et al. Among authors: stevenson aj. Oncogenesis. 2021 May 15;10(5):41. doi: 10.1038/s41389-021-00329-8. Oncogenesis. 2021. PMID: 33993200 Free PMC article.

8

Melanoma mutations modify melanocyte dynamics in co-culture with keratinocytes or fibroblasts.

Škalamera D, Stevenson AJ, Ehmann A, Ainger SA, Lanagan C, Sturm RA, Gabrielli B. Škalamera D, et al. Among authors: stevenson aj. J Cell Sci. 2019 Dec 13;132(24):jcs234716. doi: 10.1242/jcs.234716. J Cell Sci. 2019. PMID: 31767623

9

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer.

Škalamera D, Dahmer-Heath M, Stevenson AJ, Pinto C, Shah ET, Daignault SM, Said NA, Davis M, Haass NK, Williams ED, Hollier BG, Thompson EW, Gabrielli B, Gonda TJ. Škalamera D, et al. Among authors: stevenson aj. Oncotarget. 2016 Sep 20;7(38):61000-61020. doi: 10.18632/oncotarget.11314. Oncotarget. 2016. PMID: 27876705 Free PMC article.

10

Decatenation checkpoint-defective melanomas are dependent on PI3K for survival.

Brooks K, Ranall M, Spoerri L, Stevenson A, Gunasingh G, Pavey S, Meunier F, Gonda TJ, Gabrielli B. Brooks K, et al. Pigment Cell Melanoma Res. 2014 Sep;27(5):813-21. doi: 10.1111/pcmr.12268. Epub 2014 Jun 23. Pigment Cell Melanoma Res. 2014. PMID: 24890688

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