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AAV-mediated delivery of actoxumab and bezlotoxumab results in serum and mucosal antibody concentrations that provide protection from C. difficile toxin challenge.
Gene Ther. 2023 May;30(5):455-462. doi: 10.1038/s41434-021-00236-y. Epub 2021 Feb 19.
Gene Ther. 2023.
PMID: 33608675
Production of Adeno-Associated Virus Vectors in Cell Stacks for Preclinical Studies in Large Animal Models.
Rghei AD, Stevens BAY, Thomas SP, Yates JGE, McLeod BM, Karimi K, Susta L, Bridle BW, Wootton SK.
Rghei AD, et al. Among authors: stevens bay.
J Vis Exp. 2021 Jun 30;(172). doi: 10.3791/62727.
J Vis Exp. 2021.
PMID: 34279499
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Safety and Tolerability of the Adeno-Associated Virus Vector, AAV6.2FF, Expressing a Monoclonal Antibody in Murine and Ovine Animal Models.
Rghei AD, van Lieshout LP, McLeod BM, Pei Y, Lopes JA, Zielinska N, Baracuhy EM, Stevens BAY, Thomas SP, Yates JGE, Warner BM, Kobasa D, Fausther-Bovendo H, Kobinger GP, Karimi K, Thompson B, Bridle BW, Susta L, Wootton SK.
Rghei AD, et al. Among authors: stevens bay.
Biomedicines. 2021 Sep 9;9(9):1186. doi: 10.3390/biomedicines9091186.
Biomedicines. 2021.
PMID: 34572372
Free PMC article.
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AAV-Vectored Expression of the Vascular Normalizing Agents 3TSR and Fc3TSR, and the Anti-Angiogenic Bevacizumab Extends Survival in a Murine Model of End-Stage Epithelial Ovarian Carcinoma.
Stegelmeier AA, Santry LA, Guilleman MM, Matuszewska K, Minott JA, Yates JGE, Stevens BAY, Thomas SP, Vanderkamp S, Hanada K, Pei Y, Rghei AD, van Vloten JP, Pereira M, Thompson B, Major PP, Petrik JJ, Bridle BW, Wootton SK.
Stegelmeier AA, et al. Among authors: stevens bay.
Biomedicines. 2022 Feb 2;10(2):362. doi: 10.3390/biomedicines10020362.
Biomedicines. 2022.
PMID: 35203573
Free PMC article.
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AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery.
Yu DL, van Lieshout LP, Stevens BAY, Near KJJ, Stodola JK, Stinson KJ, Slavic D, Wootton SK.
Yu DL, et al. Among authors: stevens bay.
Viruses. 2023 Dec 29;16(1):57. doi: 10.3390/v16010057.
Viruses. 2023.
PMID: 38257756
Free PMC article.
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AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumonia.
Lopes JA, Garnier NE, Pei Y, Yates JGE, Campbell ESB, Goens MM, Hughes ME, Rghei AD, Stevens BAY, Guilleman MM, Thompson B, Khursigara CM, Susta L, Wootton SK.
Lopes JA, et al. Among authors: stevens bay.
Gene Ther. 2024 Apr 27. doi: 10.1038/s41434-024-00453-1. Online ahead of print.
Gene Ther. 2024.
PMID: 38678160
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