Stevens AM - Search Results

1

Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor.

Feng Y, Likos JJ, Zhu L, Woodward H, Munie G, McDonald JJ, Stevens AM, Howard CP, De Crescenzo GA, Welsch D, Shieh HS, Stallings WC. Feng Y, et al. Among authors: stevens am. Biochim Biophys Acta. 2002 Jul 29;1598(1-2):10-23. doi: 10.1016/s0167-4838(02)00307-2. Biochim Biophys Acta. 2002. PMID: 12147339

2

Synthesis and identification of conformationally constrained selective MMP inhibitors.

Freskos JN, McDonald JJ, Mischke BV, Mullins PB, Shieh HS, Stegeman RA, Stevens AM. Freskos JN, et al. Among authors: stevens am. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1757-60. doi: 10.1016/s0960-894x(99)00285-1. Bioorg Med Chem Lett. 1999. PMID: 10406637

3

Synthesis and activity of selective MMP inhibitors with an aryl backbone.

Barta TE, Becker DP, Bedell LJ, De Crescenzo GA, McDonald JJ, Munie GE, Rao S, Shieh HS, Stegeman R, Stevens AM, Villamil CI. Barta TE, et al. Among authors: stevens am. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2815-7. doi: 10.1016/s0960-894x(00)00584-9. Bioorg Med Chem Lett. 2000. PMID: 11133099

4

Polymer-assisted solution-phase library synthesis and crystal structure of alpha-ketothiazoles as tissue factor VIIa inhibitors.

Parlow JJ, Dice TA, Lachance RM, Girard TJ, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, South MS. Parlow JJ, et al. Among authors: stevens am. J Med Chem. 2003 Sep 11;46(19):4043-9. doi: 10.1021/jm030130t. J Med Chem. 2003. PMID: 12954057

5

Synthesis and crystal structures of substituted benzenes and benzoquinones as tissue factor VIIa inhibitors.

Parlow JJ, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, South MS. Parlow JJ, et al. Among authors: stevens am. J Med Chem. 2003 Sep 25;46(20):4297-312. doi: 10.1021/jm030233b. J Med Chem. 2003. PMID: 13678408

6

Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue factor VIIa complex.

Parlow JJ, Kurumbail RG, Stegeman RA, Stevens AM, Stallings WC, South MS. Parlow JJ, et al. Among authors: stevens am. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3721-5. doi: 10.1016/j.bmcl.2003.08.002. Bioorg Med Chem Lett. 2003. PMID: 14552766

7

Design, synthesis, and crystal structure of selective 2-pyridone tissue factor VIIa inhibitors.

Parlow JJ, Kurumbail RG, Stegeman RA, Stevens AM, Stallings WC, South MS. Parlow JJ, et al. Among authors: stevens am. J Med Chem. 2003 Oct 23;46(22):4696-701. doi: 10.1021/jm0301686. J Med Chem. 2003. PMID: 14561089

8

Three-dimensional structure of human cytomegalovirus protease.

Shieh HS, Kurumbail RG, Stevens AM, Stegeman RA, Sturman EJ, Pak JY, Wittwer AJ, Palmier MO, Wiegand RC, Holwerda BC, Stallings WC. Shieh HS, et al. Among authors: stevens am. Nature. 1996 Sep 19;383(6597):279-82. doi: 10.1038/383279a0. Nature. 1996. PMID: 8805708

9

Polymer-assisted solution-phase (PASP) parallel synthesis of an alpha-ketothiazole library as tissue factor VIIa inhibitors.

South MS, Dice TA, Girard TJ, Lachance RM, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, Parlow JJ. South MS, et al. Among authors: stevens am. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2363-7. doi: 10.1016/s0960-894x(03)00398-6. Bioorg Med Chem Lett. 2003. PMID: 12824035

10

Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.

South MS, Case BL, Wood RS, Jones DE, Hayes MJ, Girard TJ, Lachance RM, Nicholson NS, Clare M, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, Parlow JJ. South MS, et al. Among authors: stevens am. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2319-25. doi: 10.1016/s0960-894x(03)00410-4. Bioorg Med Chem Lett. 2003. PMID: 12824026

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