Stetson DB - Search Results

1

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

York AG, Williams KJ, Argus JP, Zhou QD, Brar G, Vergnes L, Gray EE, Zhen A, Wu NC, Yamada DH, Cunningham CR, Tarling EJ, Wilks MQ, Casero D, Gray DH, Yu AK, Wang ES, Brooks DG, Sun R, Kitchen SG, Wu TT, Reue K, Stetson DB, Bensinger SJ. York AG, et al. Among authors: stetson db. Cell. 2015 Dec 17;163(7):1716-29. doi: 10.1016/j.cell.2015.11.045. Epub 2015 Dec 10. Cell. 2015. PMID: 26686653 Free PMC article.

2

The SKIV2L RNA exosome limits activation of the RIG-I-like receptors.

Eckard SC, Rice GI, Fabre A, Badens C, Gray EE, Hartley JL, Crow YJ, Stetson DB. Eckard SC, et al. Among authors: stetson db. Nat Immunol. 2014 Sep;15(9):839-45. doi: 10.1038/ni.2948. Epub 2014 Jul 27. Nat Immunol. 2014. PMID: 25064072 Free PMC article.

3

Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome.

Gray EE, Treuting PM, Woodward JJ, Stetson DB. Gray EE, et al. Among authors: stetson db. J Immunol. 2015 Sep 1;195(5):1939-43. doi: 10.4049/jimmunol.1500969. Epub 2015 Jul 29. J Immunol. 2015. PMID: 26223655 Free PMC article.

4

DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway.

Lau L, Gray EE, Brunette RL, Stetson DB. Lau L, et al. Among authors: stetson db. Science. 2015 Oct 30;350(6260):568-71. doi: 10.1126/science.aab3291. Epub 2015 Sep 24. Science. 2015. PMID: 26405230

5

The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.

Gray EE, Winship D, Snyder JM, Child SJ, Geballe AP, Stetson DB. Gray EE, et al. Among authors: stetson db. Immunity. 2016 Aug 16;45(2):255-66. doi: 10.1016/j.immuni.2016.06.015. Epub 2016 Aug 2. Immunity. 2016. PMID: 27496731 Free PMC article.

6

Intracellular Nucleic Acid Detection in Autoimmunity.

Crowl JT, Gray EE, Pestal K, Volkman HE, Stetson DB. Crowl JT, et al. Among authors: stetson db. Annu Rev Immunol. 2017 Apr 26;35:313-336. doi: 10.1146/annurev-immunol-051116-052331. Epub 2017 Jan 30. Annu Rev Immunol. 2017. PMID: 28142323 Free PMC article. Review.

7

Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling.

Brault M, Olsen TM, Martinez J, Stetson DB, Oberst A. Brault M, et al. Among authors: stetson db. J Immunol. 2018 Apr 15;200(8):2748-2756. doi: 10.4049/jimmunol.1701492. Epub 2018 Mar 14. J Immunol. 2018. PMID: 29540580 Free PMC article.

8

Tight nuclear tethering of cGAS is essential for preventing autoreactivity.

Volkman HE, Cambier S, Gray EE, Stetson DB. Volkman HE, et al. Among authors: stetson db. Elife. 2019 Dec 6;8:e47491. doi: 10.7554/eLife.47491. Elife. 2019. PMID: 31808743 Free PMC article.

9

Universal Principled Review: A Community-Driven Method to Improve Peer Review.

Krummel M, Blish C, Kuhns M, Cadwell K, Oberst A, Goldrath A, Ansel KM, Chi H, O'Connell R, Wherry EJ, Pepper M; Future Immunology Consortium. Krummel M, et al. Cell. 2019 Dec 12;179(7):1441-1445. doi: 10.1016/j.cell.2019.11.029. Cell. 2019. PMID: 31835023 Free article.

10

Computational design of constitutively active cGAS.

Dowling QM, Volkman HE, Gray EE, Ovchinnikov S, Cambier S, Bera AK, Sankaran B, Johnson MR, Bick MJ, Kang A, Stetson DB, King NP. Dowling QM, et al. Among authors: stetson db. Nat Struct Mol Biol. 2023 Jan;30(1):72-80. doi: 10.1038/s41594-022-00862-z. Epub 2023 Jan 2. Nat Struct Mol Biol. 2023. PMID: 36593311

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