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CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy.
Fry TJ, Shah NN, Orentas RJ, Stetler-Stevenson M, Yuan CM, Ramakrishna S, Wolters P, Martin S, Delbrook C, Yates B, Shalabi H, Fountaine TJ, Shern JF, Majzner RG, Stroncek DF, Sabatino M, Feng Y, Dimitrov DS, Zhang L, Nguyen S, Qin H, Dropulic B, Lee DW, Mackall CL. Fry TJ, et al. Nat Med. 2018 Jan;24(1):20-28. doi: 10.1038/nm.4441. Epub 2017 Nov 20. Nat Med. 2018. PMID: 29155426 Free PMC article. Clinical Trial.
A phase I study of combination therapy with immunotoxins IgG-HD37-deglycosylated ricin A chain (dgA) and IgG-RFB4-dgA (Combotox) in patients with refractory CD19(+), CD22(+) B cell lymphoma.
Messmann RA, Vitetta ES, Headlee D, Senderowicz AM, Figg WD, Schindler J, Michiel DF, Creekmore S, Steinberg SM, Kohler D, Jaffe ES, Stetler-Stevenson M, Chen H, Ghetie V, Sausville EA. Messmann RA, et al. Clin Cancer Res. 2000 Apr;6(4):1302-13. Clin Cancer Res. 2000. PMID: 10778955 Clinical Trial.
PRAME expression in hairy cell leukemia.
Arons E, Suntum T, Margulies I, Yuan C, Stetler-Stevenson M, Kreitman RJ. Arons E, et al. Leuk Res. 2008 Sep;32(9):1400-6. doi: 10.1016/j.leukres.2007.12.010. Epub 2008 Mar 4. Leuk Res. 2008. PMID: 18295331 Free PMC article.
Soluble CD22 as a tumor marker for hairy cell leukemia.
Matsushita K, Margulies I, Onda M, Nagata S, Stetler-Stevenson M, Kreitman RJ. Matsushita K, et al. Blood. 2008 Sep 15;112(6):2272-7. doi: 10.1182/blood-2008-01-131987. Epub 2008 Jul 2. Blood. 2008. PMID: 18596230 Free PMC article.
244 results