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The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors.
Langdon CG, Held MA, Platt JT, Meeth K, Iyidogan P, Mamillapalli R, Koo AB, Klein M, Liu Z, Bosenberg MW, Stern DF. Langdon CG, et al. Among authors: stern df. Pigment Cell Melanoma Res. 2015 Jul;28(4):417-30. doi: 10.1111/pcmr.12376. Epub 2015 May 6. Pigment Cell Melanoma Res. 2015. PMID: 25854919 Free PMC article.
PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets.
Scortegagna M, Lau E, Zhang T, Feng Y, Sereduk C, Yin H, De SK, Meeth K, Platt JT, Langdon CG, Halaban R, Pellecchia M, Davies MA, Brown K, Stern DF, Bosenberg M, Ronai ZA. Scortegagna M, et al. Among authors: stern df. Cancer Res. 2015 Apr 1;75(7):1399-412. doi: 10.1158/0008-5472.CAN-14-2785. Epub 2015 Feb 24. Cancer Res. 2015. PMID: 25712345 Free PMC article.
A Computational Approach for Identifying Synergistic Drug Combinations.
Gayvert KM, Aly O, Platt J, Bosenberg MW, Stern DF, Elemento O. Gayvert KM, et al. Among authors: stern df. PLoS Comput Biol. 2017 Jan 13;13(1):e1005308. doi: 10.1371/journal.pcbi.1005308. eCollection 2017 Jan. PLoS Comput Biol. 2017. PMID: 28085880 Free PMC article.
139 results