Steptoe RJ - Search Results

1

Islet-specific CD8⁺ T cells gain effector function in the gut lymphoid tissues via bystander activation not molecular mimicry.

Okada M, Zhang V, Loaiza Naranjo JD, Tillett BJ, Wong FS, Steptoe RJ, Bergot AS, Hamilton-Williams EE. Okada M, et al. Among authors: steptoe rj. Immunol Cell Biol. 2023 Jan;101(1):36-48. doi: 10.1111/imcb.12593. Epub 2022 Nov 1. Immunol Cell Biol. 2023. PMID: 36214093 Free PMC article.

2

APC-targeted proinsulin expression inactivates insulin-specific memory CD8⁺ T cells in NOD mice.

Reeves PL, Rudraraju R, Liu X, Wong FS, Hamilton-Williams EE, Steptoe RJ. Reeves PL, et al. Among authors: steptoe rj. Immunol Cell Biol. 2017 Oct;95(9):765-774. doi: 10.1038/icb.2017.48. Epub 2017 Jun 14. Immunol Cell Biol. 2017. PMID: 28611473

3

Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8⁺ T-cell priming to tolerance in autoimmune-prone NOD mice.

Reeves PLS, Rudraraju R, Wong FS, Hamilton-Williams EE, Steptoe RJ. Reeves PLS, et al. Among authors: steptoe rj. Eur J Immunol. 2017 Sep;47(9):1550-1561. doi: 10.1002/eji.201747089. Epub 2017 Jul 18. Eur J Immunol. 2017. PMID: 28665492 Free article.

4

Tolerance induction by liposomes targeting a single CD8 epitope IGRP_206-214 in a model of type 1 diabetes is impeded by co-targeting a CD4⁺ islet epitope.

Buckle I, Loaiza Naranjo JD, Bergot AS, Zhang V, Talekar M, Steptoe RJ, Thomas R, Hamilton-Williams EE. Buckle I, et al. Among authors: steptoe rj. Immunol Cell Biol. 2022 Jan;100(1):33-48. doi: 10.1111/imcb.12506. Epub 2021 Nov 9. Immunol Cell Biol. 2022. PMID: 34668580

5

HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions.

Bergot AS, Monnet N, Le Tran S, Mittal D, Al-Kouba J, Steptoe RJ, Grimbaldeston MA, Frazer IH, Wells JW. Bergot AS, et al. Among authors: steptoe rj. Immunol Cell Biol. 2015 Jul;93(6):540-7. doi: 10.1038/icb.2014.123. Epub 2015 Jan 20. Immunol Cell Biol. 2015. PMID: 25601274 Free PMC article.

6

Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice.

James CR, Buckle I, Muscate F, Otsuka M, Nakao M, Oon JSh, Steptoe RJ, Thomas R, Hamilton-Williams EE. James CR, et al. Among authors: steptoe rj. Immunol Cell Biol. 2016 May;94(5):509-19. doi: 10.1038/icb.2016.7. Epub 2016 Jan 14. Immunol Cell Biol. 2016. PMID: 26763864

7

Maintenance of peripheral tolerance to islet antigens.

Hamilton-Williams EE, Bergot AS, Reeves PL, Steptoe RJ. Hamilton-Williams EE, et al. Among authors: steptoe rj. J Autoimmun. 2016 Aug;72:118-25. doi: 10.1016/j.jaut.2016.05.009. Epub 2016 May 30. J Autoimmun. 2016. PMID: 27255733 Review.

8

Regulatory T cells prevent inducible BALT formation by dampening neutrophilic inflammation.

Foo SY, Zhang V, Lalwani A, Lynch JP, Zhuang A, Lam CE, Foster PS, King C, Steptoe RJ, Mazzone SB, Sly PD, Phipps S. Foo SY, et al. Among authors: steptoe rj. J Immunol. 2015 May 1;194(9):4567-76. doi: 10.4049/jimmunol.1400909. Epub 2015 Mar 25. J Immunol. 2015. PMID: 25810394

9

Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma.

Lynch JP, Werder RB, Curren BF, Sikder MAA, Ullah A, Sebina I, Rashid RB, Zhang V, Upham JW, Hill GR, Steptoe RJ, Phipps S. Lynch JP, et al. Among authors: steptoe rj. Mucosal Immunol. 2020 Jul;13(4):652-664. doi: 10.1038/s41385-020-0268-8. Epub 2020 Feb 17. Mucosal Immunol. 2020. PMID: 32066837 Free article.

10

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling.

Loh Z, Simpson J, Ullah A, Zhang V, Gan WJ, Lynch JP, Werder RB, Sikder AA, Lane K, Sim CB, Porrello E, Mazzone SB, Sly PD, Steptoe RJ, Spann KM, Sukkar MB, Upham JW, Phipps S. Loh Z, et al. Among authors: steptoe rj. PLoS Pathog. 2020 Jul 13;16(7):e1008651. doi: 10.1371/journal.ppat.1008651. eCollection 2020 Jul. PLoS Pathog. 2020. PMID: 32658914 Free PMC article.

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