Steptoe RJ - Search Results

1

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy.

Coleman MA, Bridge JA, Lane SW, Dixon CM, Hill GR, Wells JW, Thomas R, Steptoe RJ. Coleman MA, et al. Among authors: steptoe rj. Blood. 2013 Feb 7;121(6):1049-58. doi: 10.1182/blood-2012-06-434100. Epub 2012 Dec 11. Blood. 2013. PMID: 23233664 Free article.

2

Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses.

Kenna TJ, Thomas R, Steptoe RJ. Kenna TJ, et al. Among authors: steptoe rj. Blood. 2008 Feb 15;111(4):2091-100. doi: 10.1182/blood-2007-07-103200. Epub 2007 Nov 14. Blood. 2008. PMID: 18003887 Free article.

3

Steady-state antigen-expressing dendritic cells terminate CD4+ memory T-cell responses.

Nasreen M, Waldie TM, Dixon CM, Steptoe RJ. Nasreen M, et al. Among authors: steptoe rj. Eur J Immunol. 2010 Jul;40(7):2016-25. doi: 10.1002/eji.200940085. Eur J Immunol. 2010. PMID: 20405475 Free article.

4

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets.

Markey KA, Koyama M, Kuns RD, Lineburg KE, Wilson YA, Olver SD, Raffelt NC, Don AL, Varelias A, Robb RJ, Cheong M, Engwerda CR, Steptoe RJ, Ramshaw HS, Lopez AF, Vega-Ramos J, Lew AM, Villadangos JA, Hill GR, MacDonald KP. Markey KA, et al. Among authors: steptoe rj. Blood. 2012 Jun 14;119(24):5918-30. doi: 10.1182/blood-2011-12-398164. Epub 2012 Mar 13. Blood. 2012. PMID: 22415754 Free article.

5

Re-educating immunity in respiratory allergies: the potential for hematopoietic stem cell-mediated gene therapy.

Brooks JF, Davies JM, Wells JW, Steptoe RJ. Brooks JF, et al. Among authors: steptoe rj. J Mol Med (Berl). 2018 Jan;96(1):21-30. doi: 10.1007/s00109-017-1611-8. Epub 2017 Nov 17. J Mol Med (Berl). 2018. PMID: 29150718 Review.

6

Transfer of antigen-encoding bone marrow under immune-preserving conditions deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production.

Brooks JF, Barber JEM, Davies JM, Wells JW, Steptoe RJ. Brooks JF, et al. Among authors: steptoe rj. Cytotherapy. 2020 Aug;22(8):436-444. doi: 10.1016/j.jcyt.2020.04.041. Epub 2020 Jun 13. Cytotherapy. 2020. PMID: 32546362

7

Induction of antigen-specific tolerance through hematopoietic stem cell-mediated gene therapy: the future for therapy of autoimmune disease?

Coleman MA, Steptoe RJ. Coleman MA, et al. Among authors: steptoe rj. Autoimmun Rev. 2012 Dec;12(2):195-203. doi: 10.1016/j.autrev.2011.08.012. Epub 2012 Oct 6. Autoimmun Rev. 2012. PMID: 23047179 Review.

8

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection.

Doan T, McNally A, Thomas R, Steptoe RJ. Doan T, et al. Among authors: steptoe rj. Immunol Cell Biol. 2009 Nov-Dec;87(8):615-22. doi: 10.1038/icb.2009.46. Epub 2009 Jul 7. Immunol Cell Biol. 2009. PMID: 19581919

9

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function.

Kenna TJ, Waldie T, McNally A, Thomson M, Yagita H, Thomas R, Steptoe RJ. Kenna TJ, et al. Among authors: steptoe rj. J Immunol. 2010 Jan 15;184(2):598-606. doi: 10.4049/jimmunol.0900032. Epub 2009 Dec 7. J Immunol. 2010. PMID: 19995901

10

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis.

McNally A, Hill GR, Sparwasser T, Thomas R, Steptoe RJ. McNally A, et al. Among authors: steptoe rj. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7529-34. doi: 10.1073/pnas.1103782108. Epub 2011 Apr 18. Proc Natl Acad Sci U S A. 2011. PMID: 21502514 Free PMC article.

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