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Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3.
Kornienko J, Rodríguez-Martínez M, Fenzl K, Hinze F, Schraivogel D, Grosch M, Tunaj B, Lindenhofer D, Schraft L, Kueblbeck M, Smith E, Mao C, Brown E, Owens A, Saguner AM, Meder B, Parikh V, Gotthardt M, Steinmetz LM. Kornienko J, et al. Among authors: steinmetz lm. Nat Commun. 2023 Jul 18;14(1):4312. doi: 10.1038/s41467-023-39965-6. Nat Commun. 2023. PMID: 37463913 Free PMC article.
Cardiac splicing as a diagnostic and therapeutic target.
Gotthardt M, Badillo-Lisakowski V, Parikh VN, Ashley E, Furtado M, Carmo-Fonseca M, Schudy S, Meder B, Grosch M, Steinmetz L, Crocini C, Leinwand L. Gotthardt M, et al. Nat Rev Cardiol. 2023 Aug;20(8):517-530. doi: 10.1038/s41569-022-00828-0. Epub 2023 Jan 18. Nat Rev Cardiol. 2023. PMID: 36653465 Review.
Atlas of mRNA translation and decay for bacteria.
Huch S, Nersisyan L, Ropat M, Barrett D, Wu M, Wang J, Valeriano VD, Vardazaryan N, Huerta-Cepas J, Wei W, Du J, Steinmetz LM, Engstrand L, Pelechano V. Huch S, et al. Among authors: steinmetz lm. Nat Microbiol. 2023 Jun;8(6):1123-1136. doi: 10.1038/s41564-023-01393-z. Epub 2023 May 22. Nat Microbiol. 2023. PMID: 37217719 Free PMC article.
Cell sorters see things more clearly now.
Schraivogel D, Steinmetz LM. Schraivogel D, et al. Among authors: steinmetz lm. Mol Syst Biol. 2023 Mar 9;19(3):e11254. doi: 10.15252/msb.202211254. Epub 2023 Feb 13. Mol Syst Biol. 2023. PMID: 36779527 Free PMC article.
Pooled Genome-Scale CRISPR Screens in Single Cells.
Schraivogel D, Steinmetz LM, Parts L. Schraivogel D, et al. Among authors: steinmetz lm. Annu Rev Genet. 2023 Nov 27;57:223-244. doi: 10.1146/annurev-genet-072920-013842. Epub 2023 Aug 10. Annu Rev Genet. 2023. PMID: 37562410 Free article. Review.
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Jackow J, Rami A, Hansen C, Guo Z, Gaddam S, Pappalardo A, Li L, Cramer A, Roy KR, Nguyen TM, Tanabe K, McGrath PS, Bruckner A, Bilousova G, Roop D, Bailey I, Tang JY, Christiano A, Steinmetz LM, Wernig M, Oro AE. Neumayer G, et al. Among authors: steinmetz lm. bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.529447. doi: 10.1101/2023.02.28.529447. bioRxiv. 2023. PMID: 36909618 Free PMC article. Preprint.
Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains.
McCulloch LH, Sambasivam V, Hughes AL, Annaluru N, Ramalingam S, Fanfani V, Lobzaev E, Mitchell LA, Cai J; Build-A-Genome Class; Jiang H, LaCava J, Taylor MS, Bishai WR, Stracquadanio G, Steinmetz LM, Bader JS, Zhang W, Boeke JD, Chandrasegaran S. McCulloch LH, et al. Among authors: steinmetz lm. Cell Genom. 2023 Nov 9;3(11):100419. doi: 10.1016/j.xgen.2023.100419. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020974 Free PMC article.
206 results