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119 results

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Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling.
Illi B, Dello Russo C, Colussi C, Rosati J, Pallaoro M, Spallotta F, Rotili D, Valente S, Ragone G, Martelli F, Biglioli P, Steinkuhler C, Gallinari P, Mai A, Capogrossi MC, Gaetano C. Illi B, et al. Among authors: steinkuhler c. Circ Res. 2008 Jan 4;102(1):51-8. doi: 10.1161/CIRCRESAHA.107.157305. Epub 2007 Nov 1. Circ Res. 2008. PMID: 17975112
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment.
Colussi C, Mozzetta C, Gurtner A, Illi B, Rosati J, Straino S, Ragone G, Pescatori M, Zaccagnini G, Antonini A, Minetti G, Martelli F, Piaggio G, Gallinari P, Steinkuhler C, Clementi E, Dell'Aversana C, Altucci L, Mai A, Capogrossi MC, Puri PL, Gaetano C. Colussi C, et al. Among authors: steinkuhler c. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19183-7. doi: 10.1073/pnas.0805514105. Epub 2008 Dec 1. Proc Natl Acad Sci U S A. 2008. PMID: 19047631 Free PMC article.
PP2A regulates HDAC4 nuclear import.
Paroni G, Cernotta N, Dello Russo C, Gallinari P, Pallaoro M, Foti C, Talamo F, Orsatti L, Steinkühler C, Brancolini C. Paroni G, et al. Among authors: steinkuhler c. Mol Biol Cell. 2008 Feb;19(2):655-67. doi: 10.1091/mbc.e07-06-0623. Epub 2007 Nov 28. Mol Biol Cell. 2008. PMID: 18045992 Free PMC article.
Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.
Lahm A, Paolini C, Pallaoro M, Nardi MC, Jones P, Neddermann P, Sambucini S, Bottomley MJ, Lo Surdo P, Carfí A, Koch U, De Francesco R, Steinkühler C, Gallinari P. Lahm A, et al. Among authors: steinkuhler c. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17335-40. doi: 10.1073/pnas.0706487104. Epub 2007 Oct 23. Proc Natl Acad Sci U S A. 2007. PMID: 17956988 Free PMC article.
Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor.
Vannini A, Volpari C, Filocamo G, Casavola EC, Brunetti M, Renzoni D, Chakravarty P, Paolini C, De Francesco R, Gallinari P, Steinkühler C, Di Marco S. Vannini A, et al. Among authors: steinkuhler c. Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15064-9. doi: 10.1073/pnas.0404603101. Epub 2004 Oct 11. Proc Natl Acad Sci U S A. 2004. PMID: 15477595 Free PMC article.
Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain.
Bottomley MJ, Lo Surdo P, Di Giovine P, Cirillo A, Scarpelli R, Ferrigno F, Jones P, Neddermann P, De Francesco R, Steinkühler C, Gallinari P, Carfí A. Bottomley MJ, et al. Among authors: steinkuhler c. J Biol Chem. 2008 Sep 26;283(39):26694-704. doi: 10.1074/jbc.M803514200. Epub 2008 Jul 8. J Biol Chem. 2008. PMID: 18614528 Free PMC article.
119 results