Steinhorn B - Search Results

1

Chemogenetic Approaches to Probe Redox Pathways: Implications for Cardiovascular Pharmacology and Toxicology.

Steinhorn B, Eroglu E, Michel T. Steinhorn B, et al. Annu Rev Pharmacol Toxicol. 2022 Jan 6;62:551-571. doi: 10.1146/annurev-pharmtox-012221-082339. Epub 2021 Sep 16. Annu Rev Pharmacol Toxicol. 2022. PMID: 34530645 Free PMC article.

2

Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium.

Kalwa H, Sartoretto JL, Martinelli R, Romero N, Steinhorn BS, Tao M, Ozaki CK, Carman CV, Michel T. Kalwa H, et al. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3383-8. doi: 10.1073/pnas.1320854111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550450 Free PMC article.

3

Nitroglycerin and Nitric Oxide--A Rondo of Themes in Cardiovascular Therapeutics.

Steinhorn BS, Loscalzo J, Michel T. Steinhorn BS, et al. N Engl J Med. 2015 Jul 16;373(3):277-80. doi: 10.1056/NEJMsr1503311. N Engl J Med. 2015. PMID: 26176386 Free PMC article. No abstract available.

4

Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4.

Steinhorn B, Sartoretto JL, Sorrentino A, Romero N, Kalwa H, Abel ED, Michel T. Steinhorn B, et al. Free Radic Biol Med. 2017 Dec;113:16-25. doi: 10.1016/j.freeradbiomed.2017.09.006. Epub 2017 Sep 14. Free Radic Biol Med. 2017. PMID: 28917508 Free PMC article.

5

Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction.

Steinhorn B, Sorrentino A, Badole S, Bogdanova Y, Belousov V, Michel T. Steinhorn B, et al. Nat Commun. 2018 Oct 2;9(1):4044. doi: 10.1038/s41467-018-06533-2. Nat Commun. 2018. PMID: 30279532 Free PMC article.

6

Which Antioxidant System Shapes Intracellular H₂O₂ Gradients?

Mishina NM, Bogdanova YA, Ermakova YG, Panova AS, Kotova DA, Bilan DS, Steinhorn B, Arnér ESJ, Michel T, Belousov VV. Mishina NM, et al. Among authors: steinhorn b. Antioxid Redox Signal. 2019 Sep 20;31(9):664-670. doi: 10.1089/ars.2018.7697. Epub 2019 Apr 24. Antioxid Redox Signal. 2019. PMID: 30864831 Free PMC article.

7

Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress.

Sorrentino A, Steinhorn B, Troncone L, Saravi SSS, Badole S, Eroglu E, Kijewski MF, Divakaran S, Di Carli M, Michel T. Sorrentino A, et al. Among authors: steinhorn b. Am J Physiol Heart Circ Physiol. 2019 Sep 1;317(3):H617-H626. doi: 10.1152/ajpheart.00177.2019. Epub 2019 Jul 12. Am J Physiol Heart Circ Physiol. 2019. PMID: 31298558 Free PMC article.

8

Discordance between eNOS phosphorylation and activation revealed by multispectral imaging and chemogenetic methods.

Eroglu E, Saravi SSS, Sorrentino A, Steinhorn B, Michel T. Eroglu E, et al. Among authors: steinhorn b. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):20210-20217. doi: 10.1073/pnas.1910942116. Epub 2019 Sep 16. Proc Natl Acad Sci U S A. 2019. PMID: 31527268 Free PMC article.

9

Differential endothelial signaling responses elicited by chemogenetic H₂O₂ synthesis.

Saeedi Saravi SS, Eroglu E, Waldeck-Weiermair M, Sorrentino A, Steinhorn B, Belousov V, Michel T. Saeedi Saravi SS, et al. Among authors: steinhorn b. Redox Biol. 2020 Sep;36:101605. doi: 10.1016/j.redox.2020.101605. Epub 2020 Jun 16. Redox Biol. 2020. PMID: 32590330 Free PMC article.

10

Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide.

Montiel V, Bella R, Michel LYM, Esfahani H, De Mulder D, Robinson EL, Deglasse JP, Tiburcy M, Chow PH, Jonas JC, Gilon P, Steinhorn B, Michel T, Beauloye C, Bertrand L, Farah C, Dei Zotti F, Debaix H, Bouzin C, Brusa D, Horman S, Vanoverschelde JL, Bergmann O, Gilis D, Rooman M, Ghigo A, Geninatti-Crich S, Yool A, Zimmermann WH, Roderick HL, Devuyst O, Balligand JL. Montiel V, et al. Among authors: steinhorn b. Sci Transl Med. 2020 Oct 7;12(564):eaay2176. doi: 10.1126/scitranslmed.aay2176. Sci Transl Med. 2020. PMID: 33028705

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