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A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway.
Praetorius C, Grill C, Stacey SN, Metcalf AM, Gorkin DU, Robinson KC, Van Otterloo E, Kim RS, Bergsteinsdottir K, Ogmundsdottir MH, Magnusdottir E, Mishra PJ, Davis SR, Guo T, Zaidi MR, Helgason AS, Sigurdsson MI, Meltzer PS, Merlino G, Petit V, Larue L, Loftus SK, Adams DR, Sobhiafshar U, Emre NC, Pavan WJ, Cornell R, Smith AG, McCallion AS, Fisher DE, Stefansson K, Sturm RA, Steingrimsson E. Praetorius C, et al. Among authors: steingrimsson e. Cell. 2013 Nov 21;155(5):1022-33. doi: 10.1016/j.cell.2013.10.022. Cell. 2013. PMID: 24267888 Free PMC article.
Meningeal Melanocytes in the Mouse: Distribution and Dependence on Mitf.
Gudjohnsen SA, Atacho DA, Gesbert F, Raposo G, Hurbain I, Larue L, Steingrimsson E, Petersen PH. Gudjohnsen SA, et al. Among authors: steingrimsson e. Front Neuroanat. 2015 Nov 25;9:149. doi: 10.3389/fnana.2015.00149. eCollection 2015. Front Neuroanat. 2015. PMID: 26635543 Free PMC article.
MITF has a central role in regulating starvation-induced autophagy in melanoma.
Möller K, Sigurbjornsdottir S, Arnthorsson AO, Pogenberg V, Dilshat R, Fock V, Brynjolfsdottir SH, Bindesboll C, Bessadottir M, Ogmundsdottir HM, Simonsen A, Larue L, Wilmanns M, Thorsson V, Steingrimsson E, Ogmundsdottir MH. Möller K, et al. Among authors: steingrimsson e. Sci Rep. 2019 Jan 31;9(1):1055. doi: 10.1038/s41598-018-37522-6. Sci Rep. 2019. PMID: 30705290 Free PMC article.
Melanoma Risk and Melanocyte Biology.
Bertrand JU, Steingrimsson E, Jouenne F, Bressac-de Paillerets B, Larue L. Bertrand JU, et al. Among authors: steingrimsson e. Acta Derm Venereol. 2020 Jun 3;100(11):adv00139. doi: 10.2340/00015555-3494. Acta Derm Venereol. 2020. PMID: 32346747 Free PMC article. Review.
MITF and TFEB cross-regulation in melanoma cells.
Ballesteros-Álvarez J, Dilshat R, Fock V, Möller K, Karl L, Larue L, Ögmundsdóttir MH, Steingrímsson E. Ballesteros-Álvarez J, et al. Among authors: steingrimsson e. PLoS One. 2020 Sep 3;15(9):e0238546. doi: 10.1371/journal.pone.0238546. eCollection 2020. PLoS One. 2020. PMID: 32881934 Free PMC article.
MITF reprograms the extracellular matrix and focal adhesion in melanoma.
Dilshat R, Fock V, Kenny C, Gerritsen I, Lasseur RMJ, Travnickova J, Eichhoff OM, Cerny P, Möller K, Sigurbjörnsdóttir S, Kirty K, Einarsdottir BÓ, Cheng PF, Levesque M, Cornell RA, Patton EE, Larue L, de Tayrac M, Magnúsdóttir E, Ögmundsdóttir MH, Steingrimsson E. Dilshat R, et al. Among authors: steingrimsson e. Elife. 2021 Jan 13;10:e63093. doi: 10.7554/eLife.63093. Elife. 2021. PMID: 33438577 Free PMC article.
BRN2 is a non-canonical melanoma tumor-suppressor.
Hamm M, Sohier P, Petit V, Raymond JH, Delmas V, Le Coz M, Gesbert F, Kenny C, Aktary Z, Pouteaux M, Rambow F, Sarasin A, Charoenchon N, Bellacosa A, Sanchez-Del-Campo L, Mosteo L, Lauss M, Meijer D, Steingrimsson E, Jönsson GB, Cornell RA, Davidson I, Goding CR, Larue L. Hamm M, et al. Among authors: steingrimsson e. Nat Commun. 2021 Jun 17;12(1):3707. doi: 10.1038/s41467-021-23973-5. Nat Commun. 2021. PMID: 34140478 Free PMC article.
Novel mechanisms of MITF regulation and melanoma predisposition identified in a mouse suppressor screen.
Vu HN, Valdimarsson MM, Sigurbjörnsdóttir S, Bergsteinsdóttir K, Debbache J, Bismuth K, Swing DA, Hallsson JH, Larue L, Arnheiter H, Copeland NG, Jenkins NA, Heidarsson PO, Steingrímsson E. Vu HN, et al. Among authors: steingrimsson e. bioRxiv [Preprint]. 2023 Aug 4:2023.08.04.551952. doi: 10.1101/2023.08.04.551952. bioRxiv. 2023. PMID: 37786677 Free PMC article. Preprint.
100 results