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Trimethoxy-chalcone derivatives inhibit growth of Leishmania braziliensis: synthesis, biological evaluation, molecular modeling and structure-activity relationship (SAR).
Bello ML, Chiaradia LD, Dias LR, Pacheco LK, Stumpf TR, Mascarello A, Steindel M, Yunes RA, Castro HC, Nunes RJ, Rodrigues CR. Bello ML, et al. Among authors: steindel m. Bioorg Med Chem. 2011 Aug 15;19(16):5046-52. doi: 10.1016/j.bmc.2011.06.023. Epub 2011 Jun 21. Bioorg Med Chem. 2011. PMID: 21757358
Synthesis, biological evaluation and SAR of sulfonamide 4-methoxychalcone derivatives with potential antileishmanial activity.
Andrighetti-Fröhner CR, de Oliveira KN, Gaspar-Silva D, Pacheco LK, Joussef AC, Steindel M, Simões CM, de Souza AM, Magalhaes UO, Afonso IF, Rodrigues CR, Nunes RJ, Castro HC. Andrighetti-Fröhner CR, et al. Among authors: steindel m. Eur J Med Chem. 2009 Feb;44(2):755-63. doi: 10.1016/j.ejmech.2008.04.016. Epub 2008 May 6. Eur J Med Chem. 2009. PMID: 18554753
Leishmania amazonensis growth inhibitors: biological and theoretical features of sulfonamide 4-methoxychalcone derivatives.
Souza AM, Castro HC, Brito MA, Andrighetti-Fröhner CR, Magalhães U, Oliveira KN, Gaspar-Silva D, Pacheco LK, Joussef AC, Steindel M, Simões CM, Santos DO, Albuquerque MG, Rodrigues CR, Nunes RJ. Souza AM, et al. Among authors: steindel m. Curr Microbiol. 2009 Oct;59(4):374-9. doi: 10.1007/s00284-009-9447-2. Epub 2009 Jul 23. Curr Microbiol. 2009. PMID: 19629593
Nanoemulsions containing a synthetic chalcone as an alternative for treating cutaneous leshmaniasis: optimization using a full factorial design.
de Mattos CB, Argenta DF, Melchiades Gde L, Cordeiro MN, Tonini ML, Moraes MH, Weber TB, Roman SS, Nunes RJ, Teixeira HF, Steindel M, Koester LS. de Mattos CB, et al. Among authors: steindel m. Int J Nanomedicine. 2015 Sep 1;10:5529-42. doi: 10.2147/IJN.S83929. eCollection 2015. Int J Nanomedicine. 2015. PMID: 26366075 Free PMC article.
Development of a stability-indicating LC method for determination of a synthetic chalcone derivative in a nanoemulsion dosage form and identification of the main photodegradation product by LC-MS.
Mattos CB, Deponti VB, Barreto F, Simões CM, Andrighetti-Frohner CR, Nunes RJ, Steindel M, Teixeira HF, Koester LS. Mattos CB, et al. Among authors: steindel m. J Pharm Biomed Anal. 2012 Nov;70:652-6. doi: 10.1016/j.jpba.2012.07.021. Epub 2012 Jul 27. J Pharm Biomed Anal. 2012. PMID: 22884784
Polyvinyl alcohol-based electrospun matrix as a delivery system for nanoemulsion containing chalcone against Leishmania (Leishmania) amazonensis.
Coelho D, Veleirinho B, Mazzarino L, Alberti T, Buzanello E, Oliveira RE, Yunes RA, Moraes M, Steindel M, Maraschin M. Coelho D, et al. Among authors: steindel m. Colloids Surf B Biointerfaces. 2021 Feb;198:111390. doi: 10.1016/j.colsurfb.2020.111390. Epub 2020 Oct 29. Colloids Surf B Biointerfaces. 2021. PMID: 33208279
Natural-product-inspired design and synthesis of two series of compounds active against Trypanosoma cruzi: Insights into structure-activity relationship, toxicity, and mechanism of action.
da Rosa R, Dambrós BP, Höehr de Moraes M, Grand L, Jacolot M, Popowycz F, Steindel M, Schenkel EP, Campos Bernardes LS. da Rosa R, et al. Among authors: steindel m. Bioorg Chem. 2022 Feb;119:105492. doi: 10.1016/j.bioorg.2021.105492. Epub 2021 Nov 15. Bioorg Chem. 2022. PMID: 34838333
124 results