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NOD1 activators link innate immunity to insulin resistance.
Schertzer JD, Tamrakar AK, Magalhães JG, Pereira S, Bilan PJ, Fullerton MD, Liu Z, Steinberg GR, Giacca A, Philpott DJ, Klip A. Schertzer JD, et al. Among authors: steinberg gr. Diabetes. 2011 Sep;60(9):2206-15. doi: 10.2337/db11-0004. Epub 2011 Jun 29. Diabetes. 2011. PMID: 21715553 Free PMC article.
Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis.
Crane JD, Palanivel R, Mottillo EP, Bujak AL, Wang H, Ford RJ, Collins A, Blümer RM, Fullerton MD, Yabut JM, Kim JJ, Ghia JE, Hamza SM, Morrison KM, Schertzer JD, Dyck JR, Khan WI, Steinberg GR. Crane JD, et al. Among authors: steinberg gr. Nat Med. 2015 Feb;21(2):166-72. doi: 10.1038/nm.3766. Epub 2014 Dec 8. Nat Med. 2015. PMID: 25485911 Free PMC article.
Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance.
Denou E, Lolmède K, Garidou L, Pomie C, Chabo C, Lau TC, Fullerton MD, Nigro G, Zakaroff-Girard A, Luche E, Garret C, Serino M, Amar J, Courtney M, Cavallari JF, Henriksbo BD, Barra NG, Foley KP, McPhee JB, Duggan BM, O'Neill HM, Lee AJ, Sansonetti P, Ashkar AA, Khan WI, Surette MG, Bouloumié A, Steinberg GR, Burcelin R, Schertzer JD. Denou E, et al. Among authors: steinberg gr. EMBO Mol Med. 2015 Mar;7(3):259-74. doi: 10.15252/emmm.201404169. EMBO Mol Med. 2015. PMID: 25666722 Free PMC article.
The gut microbiome regulates host glucose homeostasis via peripheral serotonin.
Martin AM, Yabut JM, Choo JM, Page AJ, Sun EW, Jessup CF, Wesselingh SL, Khan WI, Rogers GB, Steinberg GR, Keating DJ. Martin AM, et al. Among authors: steinberg gr. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19802-19804. doi: 10.1073/pnas.1909311116. Epub 2019 Sep 16. Proc Natl Acad Sci U S A. 2019. PMID: 31527237 Free PMC article.
Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK.
Banskota S, Wang H, Kwon YH, Gautam J, Gurung P, Haq S, Hassan FMN, Bowdish DM, Kim JA, Carling D, Fullerton MD, Steinberg GR, Khan WI. Banskota S, et al. Among authors: steinberg gr. Inflamm Bowel Dis. 2021 May 17;27(6):914-926. doi: 10.1093/ibd/izaa305. Inflamm Bowel Dis. 2021. PMID: 33252129 Free PMC article.
Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota.
Ahmed BA, Ong FJ, Barra NG, Blondin DP, Gunn E, Oreskovich SM, Szamosi JC, Syed SA, Hutchings EK, Konyer NB, Singh NP, Yabut JM, Desjardins EM, Anhê FF, Foley KP, Holloway AC, Noseworthy MD, Haman F, Carpentier AC, Surette MG, Schertzer JD, Punthakee Z, Steinberg GR, Morrison KM. Ahmed BA, et al. Among authors: steinberg gr. Cell Rep Med. 2021 Sep 14;2(9):100397. doi: 10.1016/j.xcrm.2021.100397. eCollection 2021 Sep 21. Cell Rep Med. 2021. PMID: 34622234 Free PMC article.
233 results