Stein SC - Search Results

1

Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8.

Kirsch P, Jakob V, Oberhausen K, Stein SC, Cucarro I, Schulz TF, Empting M. Kirsch P, et al. Among authors: stein sc. J Med Chem. 2019 Apr 25;62(8):3924-3939. doi: 10.1021/acs.jmedchem.8b01827. Epub 2019 Apr 12. J Med Chem. 2019. PMID: 30888817

2

Hit-to-lead optimization of a latency-associated nuclear antigen inhibitor against Kaposi's sarcoma-associated herpesvirus infections.

Kirsch P, Stein SC, Berwanger A, Rinkes J, Jakob V, Schulz TF, Empting M. Kirsch P, et al. Among authors: stein sc. Eur J Med Chem. 2020 Sep 15;202:112525. doi: 10.1016/j.ejmech.2020.112525. Epub 2020 Jun 28. Eur J Med Chem. 2020. PMID: 32634628 Free article.

3

Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods.

Bošnjak B, Stein SC, Willenzon S, Cordes AK, Puppe W, Bernhardt G, Ravens I, Ritter C, Schultze-Florey CR, Gödecke N, Martens J, Kleine-Weber H, Hoffmann M, Cossmann A, Yilmaz M, Pink I, Hoeper MM, Behrens GMN, Pöhlmann S, Blasczyk R, Schulz TF, Förster R. Bošnjak B, et al. Among authors: stein sc. Cell Mol Immunol. 2021 Apr;18(4):936-944. doi: 10.1038/s41423-020-00573-9. Epub 2020 Nov 2. Cell Mol Immunol. 2021. PMID: 33139905 Free PMC article.

4

Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers.

Vanshylla K, Fan C, Wunsch M, Poopalasingam N, Meijers M, Kreer C, Kleipass F, Ruchnewitz D, Ercanoglu MS, Gruell H, Münn F, Pohl K, Janicki H, Nolden T, Bartl S, Stein SC, Augustin M, Dewald F, Gieselmann L, Schommers P, Schulz TF, Sander LE, Koch M, Łuksza M, Lässig M, Bjorkman PJ, Klein F. Vanshylla K, et al. Among authors: stein sc. Cell Host Microbe. 2022 Jan 12;30(1):69-82.e10. doi: 10.1016/j.chom.2021.12.010. Epub 2021 Dec 18. Cell Host Microbe. 2022. PMID: 34973165 Free PMC article.

5

Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen: more than a key mediator of viral persistence.

Schulz TF, Freise A, Stein SC. Schulz TF, et al. Among authors: stein sc. Curr Opin Virol. 2023 Aug;61:101336. doi: 10.1016/j.coviro.2023.101336. Epub 2023 Jun 16. Curr Opin Virol. 2023. PMID: 37331160 Review.

6

Disrupting Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor.

Berwanger A, Stein SC, Kany AM, Gartner M, Loretz B, Lehr CM, Hirsch AKH, Schulz TF, Empting M. Berwanger A, et al. Among authors: stein sc. J Med Chem. 2023 Aug 10;66(15):10782-10790. doi: 10.1021/acs.jmedchem.3c00990. Epub 2023 Jul 28. J Med Chem. 2023. PMID: 37506283 Free PMC article.

7

Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis.

Stein SC, Faber E, Bats SH, Murillo T, Speidel Y, Coombs N, Josenhans C. Stein SC, et al. PLoS Pathog. 2017 Jul 17;13(7):e1006514. doi: 10.1371/journal.ppat.1006514. eCollection 2017 Jul. PLoS Pathog. 2017. PMID: 28715499 Free PMC article.

8

Contribution of Heptose Metabolites and the cag Pathogenicity Island to the Activation of Monocytes/Macrophages by Helicobacter pylori.

Faass L, Stein SC, Hauke M, Gapp M, Albanese M, Josenhans C. Faass L, et al. Among authors: stein sc. Front Immunol. 2021 May 19;12:632154. doi: 10.3389/fimmu.2021.632154. eCollection 2021. Front Immunol. 2021. PMID: 34093525 Free PMC article.

9

Innate immune activation and modulatory factors of Helicobacter pylori towards phagocytic and nonphagocytic cells.

Faass L, Hauke M, Stein SC, Josenhans C. Faass L, et al. Among authors: stein sc. Curr Opin Immunol. 2023 Jun;82:102301. doi: 10.1016/j.coi.2023.102301. Epub 2023 Mar 16. Curr Opin Immunol. 2023. PMID: 36933362 Review.

10

Innate activation of human neutrophils and neutrophil-like cells by the pro-inflammatory bacterial metabolite ADP-heptose and Helicobacter pylori.

Faass L, Hauke M, Stein SC, Josenhans C. Faass L, et al. Among authors: stein sc. Int J Med Microbiol. 2023 Jul;313(4):151585. doi: 10.1016/j.ijmm.2023.151585. Epub 2023 Jun 28. Int J Med Microbiol. 2023. PMID: 37399704 Free article.

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