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A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.
Broman MT, Nadadur RD, Perez-Cervantes C, Burnicka-Turek O, Lazarevic S, Gams A, Laforest B, Steimle JD, Iddir S, Wang Z, Smith L, Mazurek SR, Olivey HE, Zhou P, Gadek M, Shen KM, Khan Z, Theisen JWM, Yang XH, Ikegami K, Efimov IR, Pu WT, Weber CR, McNally EM, Svensson EC, Moskowitz IP. Broman MT, et al. Among authors: steimle jd. Circulation. 2024 Apr 9;149(15):1205-1230. doi: 10.1161/CIRCULATIONAHA.123.066804. Epub 2024 Jan 8. Circulation. 2024. PMID: 38189150
TBX5: A Key Regulator of Heart Development.
Steimle JD, Moskowitz IP. Steimle JD, et al. Curr Top Dev Biol. 2017;122:195-221. doi: 10.1016/bs.ctdb.2016.08.008. Epub 2016 Sep 28. Curr Top Dev Biol. 2017. PMID: 28057264 Free PMC article. Review.
Transcriptional Patterning of the Ventricular Cardiac Conduction System.
Burnicka-Turek O, Broman MT, Steimle JD, Boukens BJ, Petrenko NB, Ikegami K, Nadadur RD, Qiao Y, Arnolds DE, Yang XH, Patel VV, Nobrega MA, Efimov IR, Moskowitz IP. Burnicka-Turek O, et al. Among authors: steimle jd. Circ Res. 2020 Jul 17;127(3):e94-e106. doi: 10.1161/CIRCRESAHA.118.314460. Epub 2020 Apr 15. Circ Res. 2020. PMID: 32290757 Free PMC article.
Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.
Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP. Steimle JD, et al. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10615-E10624. doi: 10.1073/pnas.1811624115. Epub 2018 Oct 23. Proc Natl Acad Sci U S A. 2018. PMID: 30352852 Free PMC article.
Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization.
Bersell KR, Yang T, Mosley JD, Glazer AM, Hale AT, Kryshtal DO, Kim K, Steimle JD, Brown JD, Salem JE, Campbell CC, Hong CC, Wells QS, Johnson AN, Short L, Blair MA, Behr ER, Petropoulou E, Jamshidi Y, Benson MD, Keyes MJ, Ngo D, Vasan RS, Yang Q, Gerszten RE, Shaffer C, Parikh S, Sheng Q, Kannankeril PJ, Moskowitz IP, York JD, Wang TJ, Knollmann BC, Roden DM. Bersell KR, et al. Among authors: steimle jd. Circulation. 2023 Mar 7;147(10):824-840. doi: 10.1161/CIRCULATIONAHA.122.062193. Epub 2022 Dec 16. Circulation. 2023. PMID: 36524479 Free PMC article.
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages.
Rowton M, Perez-Cervantes C, Hur S, Jacobs-Li J, Lu E, Deng N, Guzzetta A, Hoffmann AD, Stocker M, Steimle JD, Lazarevic S, Oubaha S, Yang XH, Kim C, Yu S, Eckart H, Koska M, Hanson E, Chan SSK, Garry DJ, Kyba M, Basu A, Ikegami K, Pott S, Moskowitz IP. Rowton M, et al. Among authors: steimle jd. Dev Cell. 2022 Sep 26;57(18):2181-2203.e9. doi: 10.1016/j.devcel.2022.08.009. Epub 2022 Sep 14. Dev Cell. 2022. PMID: 36108627 Free PMC article.
19 results