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Primary cilia sense glutamine availability and respond via asparagine synthetase.
Nat Metab. 2023 Mar;5(3):385-397. doi: 10.1038/s42255-023-00754-6. Epub 2023 Mar 6.
Nat Metab. 2023.
PMID: 36879119
Free PMC article.
Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.
Clerici S, Podrini C, Stefanoni D, Distefano G, Cassina L, Steidl ME, Tronci L, Canu T, Chiaravalli M, Spies D, Bell TA 3rd, Costa AS, Esposito A, D'Alessandro A, Frezza C, Bachi A, Boletta A.
Clerici S, et al. Among authors: steidl me.
EMBO Mol Med. 2024 Apr 29. doi: 10.1038/s44321-024-00071-9. Online ahead of print.
EMBO Mol Med. 2024.
PMID: 38684863
Free article.
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