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Functional characterization of novel ALOX15 orthologs representing key steps in mammalian evolution supports the Evolutionary Hypothesis of reaction specificity.
Kozlov N, Humeniuk L, Ufer C, Ivanov I, Golovanov A, Stehling S, Heydeck D, Kuhn H. Kozlov N, et al. Among authors: stehling s. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Mar;1864(3):372-385. doi: 10.1016/j.bbalip.2018.12.016. Epub 2018 Dec 29. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30599203
The lipoxygenase pathway of Tupaia belangeri representing Scandentia. Genomic multiplicity and functional characterization of the ALOX15 orthologs in the tree shrew.
Schäfer M, Fan Y, Gu T, Heydeck D, Stehling S, Ivanov I, Yao YG, Kuhn H. Schäfer M, et al. Among authors: stehling s. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Feb;1865(2):158550. doi: 10.1016/j.bbalip.2019.158550. Epub 2019 Oct 29. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 31676437
A role of Gln596 in fine-tuning mammalian ALOX15 specificity, protein stability and allosteric properties.
Cruz A, Di Venere A, Mei G, Zhuravlev A, Golovanov A, Stehling S, Heydeck D, Lluch JM, González-Lafont À, Kuhn H, Ivanov I. Cruz A, et al. Among authors: stehling s. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jul;1865(7):158680. doi: 10.1016/j.bbalip.2020.158680. Epub 2020 Mar 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32151768
Eicosanoid biosynthesis in marine mammals.
Reisch F, Kakularam KR, Stehling S, Heydeck D, Kuhn H. Reisch F, et al. Among authors: stehling s. FEBS J. 2021 Feb;288(4):1387-1406. doi: 10.1111/febs.15469. Epub 2020 Jul 18. FEBS J. 2021. PMID: 32627384 Free article.
27 results