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Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation.
Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. Dagvadorj J, et al. Among authors: stehlik c. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2015632118. doi: 10.1073/pnas.2015632118. Proc Natl Acad Sci U S A. 2021. PMID: 33361152 Free PMC article.
COPs and POPs: modulators of inflammasome activity.
Stehlik C, Dorfleutner A. Stehlik C, et al. J Immunol. 2007 Dec 15;179(12):7993-8. doi: 10.4049/jimmunol.179.12.7993. J Immunol. 2007. PMID: 18056338 Free PMC article. Review.
Inflammasomes and their activation.
Khare S, Luc N, Dorfleutner A, Stehlik C. Khare S, et al. Among authors: stehlik c. Crit Rev Immunol. 2010;30(5):463-87. doi: 10.1615/critrevimmunol.v30.i5.50. Crit Rev Immunol. 2010. PMID: 21083527 Free PMC article. Review.
72 results