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Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply.
Evron Y, Colton CK, Ludwig B, Weir GC, Zimermann B, Maimon S, Neufeld T, Shalev N, Goldman T, Leon A, Yavriyants K, Shabtay N, Rozenshtein T, Azarov D, DiIenno AR, Steffen A, de Vos P, Bornstein SR, Barkai U, Rotem A. Evron Y, et al. Among authors: steffen a. Sci Rep. 2018 Apr 25;8(1):6508. doi: 10.1038/s41598-018-23862-w. Sci Rep. 2018. PMID: 29695723 Free PMC article.
Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist.
Ludwig B, Rotem A, Schmid J, Weir GC, Colton CK, Brendel MD, Neufeld T, Block NL, Yavriyants K, Steffen A, Ludwig S, Chavakis T, Reichel A, Azarov D, Zimermann B, Maimon S, Balyura M, Rozenshtein T, Shabtay N, Vardi P, Bloch K, de Vos P, Schally AV, Bornstein SR, Barkai U. Ludwig B, et al. Among authors: steffen a. Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5022-7. doi: 10.1073/pnas.1201868109. Epub 2012 Mar 5. Proc Natl Acad Sci U S A. 2012. PMID: 22393012 Free PMC article.
The efficacy of an immunoisolating membrane system for islet xenotransplantation in minipigs.
Neufeld T, Ludwig B, Barkai U, Weir GC, Colton CK, Evron Y, Balyura M, Yavriyants K, Zimermann B, Azarov D, Maimon S, Shabtay N, Rozenshtein T, Lorber D, Steffen A, Willenz U, Bloch K, Vardi P, Taube R, de Vos P, Lewis EC, Bornstein SR, Rotem A. Neufeld T, et al. Among authors: steffen a. PLoS One. 2013 Aug 1;8(8):e70150. doi: 10.1371/journal.pone.0070150. Print 2013. PLoS One. 2013. PMID: 23936385 Free PMC article.
Transplantation of human islets without immunosuppression.
Ludwig B, Reichel A, Steffen A, Zimerman B, Schally AV, Block NL, Colton CK, Ludwig S, Kersting S, Bonifacio E, Solimena M, Gendler Z, Rotem A, Barkai U, Bornstein SR. Ludwig B, et al. Among authors: steffen a. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19054-8. doi: 10.1073/pnas.1317561110. Epub 2013 Oct 28. Proc Natl Acad Sci U S A. 2013. PMID: 24167261 Free PMC article.
A novel device for islet transplantation providing immune protection and oxygen supply.
Ludwig B, Zimerman B, Steffen A, Yavriants K, Azarov D, Reichel A, Vardi P, German T, Shabtay N, Rotem A, Evron Y, Neufeld T, Mimon S, Ludwig S, Brendel MD, Bornstein SR, Barkai U. Ludwig B, et al. Among authors: steffen a. Horm Metab Res. 2010 Dec;42(13):918-22. doi: 10.1055/s-0030-1267916. Epub 2010 Oct 28. Horm Metab Res. 2010. PMID: 21031332
Agonist of growth hormone-releasing hormone as a potential effector for survival and proliferation of pancreatic islets.
Ludwig B, Ziegler CG, Schally AV, Richter C, Steffen A, Jabs N, Funk RH, Brendel MD, Block NL, Ehrhart-Bornstein M, Bornstein SR. Ludwig B, et al. Among authors: steffen a. Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12623-8. doi: 10.1073/pnas.1005098107. Epub 2010 Jun 28. Proc Natl Acad Sci U S A. 2010. PMID: 20616039 Free PMC article.
Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes.
Ludwig B, Ludwig S, Steffen A, Knauf Y, Zimerman B, Heinke S, Lehmann S, Schubert U, Schmid J, Bleyer M, Schönmann U, Colton CK, Bonifacio E, Solimena M, Reichel A, Schally AV, Rotem A, Barkai U, Grinberg-Rashi H, Kaup FJ, Avni Y, Jones P, Bornstein SR. Ludwig B, et al. Among authors: steffen a. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11745-11750. doi: 10.1073/pnas.1708420114. Epub 2017 Oct 16. Proc Natl Acad Sci U S A. 2017. PMID: 29078330 Free PMC article.
642 results