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BRAF V600E is associated with higher incidence of second cancers in adults with Langerhans cell histiocytosis.
Acosta-Medina AA, Kemps PG, Zondag TCE, Abeykoon JP, Forma-Borst J, Steenwijk EC, Feijen EAM, Teepen JC, Bennani NN, Schram SM, Shah MV, Davidge-Pitts C, Koster MJ, Ryu JH, Vassallo R, Tobin WO, Young JR, Dasari S, Rech K, Ravindran A, Cleven AHG, Verdijk RM, van Noesel CJM, Balgobind BV, Bouma GJ, Saeed P, Bramer JAM, de Groen RAL, Vermaat JSP, van de Sande MAJ, Smit EF, Langerak AW, van Wezel T, Tonino SH, van den Bos C, van Laar JAM, Go RS, Goyal G, van Halteren AGS. Acosta-Medina AA, et al. Among authors: steenwijk ec. Blood. 2023 Nov 2;142(18):1570-1575. doi: 10.1182/blood.2023021212. Blood. 2023. PMID: 37595284
Clinicogenomic associations in childhood Langerhans cell histiocytosis: an international cohort study.
Kemps PG, Zondag TCE, Arnardóttir HB, Solleveld-Westerink N, Borst J, Steenwijk EC, van Egmond D, Swennenhuis JF, Stelloo E, Trambusti I, Verdijk RM, van Noesel CJM, Cleven AHG, Scheijde-Vermeulen MA, Koudijs MJ, Krsková L, Hawkins C, Egeler RM, Brok J, von Bahr Greenwood T, Svojgr K, Beishuizen A, van Laar JAM, Pötschger U, Hutter C, Sieni E, Minkov M, Abla O, van Wezel T, van den Bos C, van Halteren AGS. Kemps PG, et al. Among authors: steenwijk ec. Blood Adv. 2023 Feb 28;7(4):664-679. doi: 10.1182/bloodadvances.2022007947. Blood Adv. 2023. PMID: 36083130 Free PMC article.
Apparent Lack of BRAFV600E Derived HLA Class I Presented Neoantigens Hampers Neoplastic Cell Targeting by CD8+ T Cells in Langerhans Cell Histiocytosis.
Kemps PG, Zondag TC, Steenwijk EC, Andriessen Q, Borst J, Vloemans S, Roelen DL, Voortman LM, Verdijk RM, van Noesel CJM, Cleven AHG, Hawkins C, Lang V, de Ru AH, Janssen GMC, Haasnoot GW, Franken KLMC, van Eijk R, Solleveld-Westerink N, van Wezel T, Egeler RM, Beishuizen A, van Laar JAM, Abla O, van den Bos C, van Veelen PA, van Halteren AGS. Kemps PG, et al. Among authors: steenwijk ec. Front Immunol. 2020 Jan 10;10:3045. doi: 10.3389/fimmu.2019.03045. eCollection 2019. Front Immunol. 2020. PMID: 31998317 Free PMC article.
Association of Increased Treg Cell Levels With Elevated Indoleamine 2,3-Dioxygenase Activity and an Imbalanced Kynurenine Pathway in Interferon-Positive Primary Sjögren's Syndrome.
Maria NI, van Helden-Meeuwsen CG, Brkic Z, Paulissen SM, Steenwijk EC, Dalm VA, van Daele PL, Martin van Hagen P, Kroese FG, van Roon JA, Harkin A, Dik WA, Drexhage HA, Lubberts E, Versnel MA. Maria NI, et al. Among authors: steenwijk ec. Arthritis Rheumatol. 2016 Jul;68(7):1688-99. doi: 10.1002/art.39629. Arthritis Rheumatol. 2016. PMID: 26866723
Systemic interferon type I and type II signatures in primary Sjögren's syndrome reveal differences in biological disease activity.
Bodewes ILA, Al-Ali S, van Helden-Meeuwsen CG, Maria NI, Tarn J, Lendrem DW, Schreurs MWJ, Steenwijk EC, van Daele PLA, Both T, Bowman SJ, Griffiths B, Ng WF; UK Primary Sjögren’s Syndrome registry; Versnel MA. Bodewes ILA, et al. Among authors: steenwijk ec. Rheumatology (Oxford). 2018 May 1;57(5):921-930. doi: 10.1093/rheumatology/kex490. Rheumatology (Oxford). 2018. PMID: 29474655
Contrasting expression pattern of RNA-sensing receptors TLR7, RIG-I and MDA5 in interferon-positive and interferon-negative patients with primary Sjögren's syndrome.
Maria NI, Steenwijk EC, IJpma AS, van Helden-Meeuwsen CG, Vogelsang P, Beumer W, Brkic Z, van Daele PL, van Hagen PM, van der Spek PJ, Drexhage HA, Versnel MA. Maria NI, et al. Among authors: steenwijk ec. Ann Rheum Dis. 2017 Apr;76(4):721-730. doi: 10.1136/annrheumdis-2016-209589. Epub 2016 Sep 26. Ann Rheum Dis. 2017. PMID: 27672125