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Bifunctional crosslinking ligands for transthyretin.
Open Biol. 2015 Sep;5(9):150105. doi: 10.1098/rsob.150105.
Open Biol. 2015.
PMID: 26400472
Free PMC article.
A new antibiotic kills pathogens without detectable resistance.
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K.
Ling LL, et al. Among authors: steadman va.
Nature. 2015 Jan 22;517(7535):455-9. doi: 10.1038/nature14098. Epub 2015 Jan 7.
Nature. 2015.
PMID: 25561178
Free PMC article.
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Drug Discovery: Collaborations between Contract Research Organizations and the Pharmaceutical Industry.
Steadman VA.
Steadman VA.
ACS Med Chem Lett. 2018 Jun 4;9(7):581-583. doi: 10.1021/acsmedchemlett.8b00236. eCollection 2018 Jul 12.
ACS Med Chem Lett. 2018.
PMID: 30034580
Free PMC article.
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Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle.
Mackman RL, Steadman VA, Dean DK, Jansa P, Poullennec KG, Appleby T, Austin C, Blakemore CA, Cai R, Cannizzaro C, Chin G, Chiva JC, Dunbar NA, Fliri H, Highton AJ, Hui H, Ji M, Jin H, Karki K, Keats AJ, Lazarides L, Lee YJ, Liclican A, Mish M, Murray B, Pettit SB, Pyun P, Sangi M, Santos R, Sanvoisin J, Schmitz U, Schrier A, Siegel D, Sperandio D, Stepan G, Tian Y, Watt GM, Yang H, Schultz BE.
Mackman RL, et al. Among authors: steadman va.
J Med Chem. 2018 Nov 8;61(21):9473-9499. doi: 10.1021/acs.jmedchem.8b00802. Epub 2018 Aug 22.
J Med Chem. 2018.
PMID: 30074795
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Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A.
Steadman VA, Pettit SB, Poullennec KG, Lazarides L, Keats AJ, Dean DK, Stanway SJ, Austin CA, Sanvoisin JA, Watt GM, Fliri HG, Liclican AC, Jin D, Wong MH, Leavitt SA, Lee YJ, Tian Y, Frey CR, Appleby TC, Schmitz U, Jansa P, Mackman RL, Schultz BE.
Steadman VA, et al.
J Med Chem. 2017 Feb 9;60(3):1000-1017. doi: 10.1021/acs.jmedchem.6b01329. Epub 2017 Jan 31.
J Med Chem. 2017.
PMID: 28075591
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Erratum: A new antibiotic kills pathogens without detectable resistance.
Ling LL, Schneider T, Peoples AJ, Spoering AL, Engels I, Conlon BP, Mueller A, Schäberle TF, Hughes DE, Epstein S, Jones M, Lazarides L, Steadman VA, Cohen DR, Felix CR, Fetterman KA, Millett WP, Nitti AG, Zullo AM, Chen C, Lewis K.
Ling LL, et al. Among authors: steadman va.
Nature. 2015 Apr 16;520(7547):388. doi: 10.1038/nature14303. Epub 2015 Feb 25.
Nature. 2015.
PMID: 25731174
No abstract available.
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Structure and reactivity of bicyclic methylene aziridines prepared by intramolecular aziridination of allenes.
Robertson J, Feast GC, White LV, Steadman VA, Claridge TD.
Robertson J, et al. Among authors: steadman va.
Org Biomol Chem. 2010 Jun 28;8(13):3060-3. doi: 10.1039/c003693e. Epub 2010 May 18.
Org Biomol Chem. 2010.
PMID: 20480094
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Unprecedented Epimerization of an Azithromycin Analogue: Synthesis, Structure and Biological Activity of 2'-Dehydroxy-5″-Epi-Azithromycin.
Kragol G, Steadman VA, Marušić Ištuk Z, Čikoš A, Bosnar M, Jelić D, Ergović G, Trzun M, Bošnjak B, Bokulić A, Padovan J, Glojnarić I, Eraković Haber V.
Kragol G, et al. Among authors: steadman va.
Molecules. 2022 Feb 3;27(3):1034. doi: 10.3390/molecules27031034.
Molecules. 2022.
PMID: 35164298
Free PMC article.
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