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Year Number of Results
2002 1
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2004 3
2008 1
2009 1
2012 3
2014 2
2015 4
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2017 2
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2019 1
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2021 1
2022 2
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Page 1
Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review.
Papapetropoulos A, Topouzis S, Alexander SPH, Cortese-Krott M, Kendall DA, Martemyanov KA, Mauro C, Nagercoil N, Panettieri RA Jr, Patel HH, Schulz R, Stefanska B, Stephens GJ, Teixeira MM, Vergnolle N, Wang X, Ferdinandy P. Papapetropoulos A, et al. Among authors: topouzis s. Br J Pharmacol. 2024 Mar 22. doi: 10.1111/bph.16337. Online ahead of print. Br J Pharmacol. 2024. PMID: 38519837 Review.
Replacement of heme by soluble guanylate cyclase (sGC) activators abolishes heme-nitric oxide/oxygen (H-NOX) domain structural plasticity.
Argyriou AI, Makrynitsa GI, Dalkas G, Georgopoulou DA, Salagiannis K, Vazoura V, Papapetropoulos A, Topouzis S, Spyroulias GA. Argyriou AI, et al. Among authors: topouzis s. Curr Res Struct Biol. 2021 Nov 18;3:324-336. doi: 10.1016/j.crstbi.2021.11.003. eCollection 2021. Curr Res Struct Biol. 2021. PMID: 34901882 Free PMC article.
Therapeutic Targeting of the Soluble Guanylate Cyclase.
Makrynitsa GI, Zompra AA, Argyriou AI, Spyroulias GA, Topouzis S. Makrynitsa GI, et al. Among authors: topouzis s. Curr Med Chem. 2019;26(15):2730-2747. doi: 10.2174/0929867326666190108095851. Curr Med Chem. 2019. PMID: 30621555 Review.
Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice.
Glynos C, Bibli SI, Katsaounou P, Pavlidou A, Magkou C, Karavana V, Topouzis S, Kalomenidis I, Zakynthinos S, Papapetropoulos A. Glynos C, et al. Among authors: topouzis s. Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L662-L672. doi: 10.1152/ajplung.00389.2017. Epub 2018 Aug 9. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 30091379 Free article.
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017.
Todd Milne G; on behalf of the Ironwood team; Sandner P, Lincoln KA, Harrison PC, Chen H, Wang H, Clifford H, Qian HS, Wong D, Sarko C, Fryer R, Richman J, Reinhart GA, Boustany CM, Pullen SS, Andresen H, Moltzau LR, Cataliotti A, Levy FO, Lukowski R, Frankenreiter S, Friebe A, Calamaras T, Baumgartner R, McLaughlin A, Aronovitz M, Baur W, Wang GR, Kapur N, Karas R, Blanton R, Hell S, Waldman SA, Lin JE, Colon-Gonzalez F, Kim GW, Blomain ES, Merlino D, Snook A, Erdmann J, Wobst J, Kessler T, Schunkert H, Walter U, Pagel O, Walter E, Gambaryan S, Smolenski A, Jurk K, Zahedi R, Klinger JR, Benza RL, Corris PA, Langleben D, Naeije R, Simonneau G, Meier C, Colorado P, Chang MK, Busse D, Hoeper MM, Masferrer JL, Jacobson S, Liu G, Sarno R, Bernier S, Zhang P, Todd Milne G, Flores-Costa R, Currie M, Hall K, Möhrle D, Reimann K, Wolter S, Wolters M, Mergia E, Eichert N, Geisler HS, Ruth P, Friebe A, Feil R, Zimmermann U, Koesling D, Knipper M, Rüttiger L, Tanaka Y, Okamoto A, Nojiri T, Kumazoe M, Tokudome T, Miura K, Hino J, Hosoda H, Miyazato M, Kangawa K, Kapil V, Ahluwalia A, Paolocci N, Eaton P, Campbell JC, Henning P, Franz E, Sankaran B, Herberg FW, Kim C, Wittwer M, Luo Q, Kaila V… See abstract for full author list ➔ Todd Milne G, et al. Among authors: topouzis s. BMC Pharmacol Toxicol. 2017 Oct 10;18(Suppl 1):64. doi: 10.1186/s40360-017-0170-5. BMC Pharmacol Toxicol. 2017. PMID: 29035170 Free PMC article. No abstract available.
Nurr1:RXRα heterodimer activation as monotherapy for Parkinson's disease.
Spathis AD, Asvos X, Ziavra D, Karampelas T, Topouzis S, Cournia Z, Qing X, Alexakos P, Smits LM, Dalla C, Rideout HJ, Schwamborn JC, Tamvakopoulos C, Fokas D, Vassilatis DK. Spathis AD, et al. Among authors: topouzis s. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3999-4004. doi: 10.1073/pnas.1616874114. Epub 2017 Mar 27. Proc Natl Acad Sci U S A. 2017. PMID: 28348207 Free PMC article.
25 results