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Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Finol-Urdaneta RK, Ziegman R, Dekan Z, McArthur JR, Heitmann S, Luna-Ramirez K, Tae HS, Mueller A, Starobova H, Chin YK, Wingerd JS, Undheim EAB, Cristofori-Armstrong B, Hill AP, Herzig V, King GF, Vetter I, Rash LD, Adams DJ, Alewood PF. Finol-Urdaneta RK, et al. Among authors: starobova h. Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):e2110932119. doi: 10.1073/pnas.2110932119. Proc Natl Acad Sci U S A. 2022. PMID: 35074873 Free PMC article.
α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors.
Mueller A, Starobova H, Inserra MC, Jin AH, Deuis JR, Dutertre S, Lewis RJ, Alewood PF, Daly NL, Vetter I. Mueller A, et al. Among authors: starobova h. Biochem Pharmacol. 2015 Mar 15;94(2):155-63. doi: 10.1016/j.bcp.2015.01.011. Epub 2015 Jan 31. Biochem Pharmacol. 2015. PMID: 25646788
NaV1.7 as a pain target - From gene to pharmacology.
Vetter I, Deuis JR, Mueller A, Israel MR, Starobova H, Zhang A, Rash LD, Mobli M. Vetter I, et al. Among authors: starobova h. Pharmacol Ther. 2017 Apr;172:73-100. doi: 10.1016/j.pharmthera.2016.11.015. Epub 2016 Dec 2. Pharmacol Ther. 2017. PMID: 27916648 Review. No abstract available.
Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions.
Mueller A, Dekan Z, Kaas Q, Agwa AJ, Starobova H, Alewood PF, Schroeder CI, Mobli M, Deuis JR, Vetter I. Mueller A, et al. Among authors: starobova h. ACS Pharmacol Transl Sci. 2020 Feb 19;3(3):535-546. doi: 10.1021/acsptsci.0c00002. eCollection 2020 Jun 12. ACS Pharmacol Transl Sci. 2020. PMID: 32566918 Free PMC article.
18 results