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Mast cell-derived BH4 is a critical mediator of postoperative pain.
Starkl P, Jonsson G, Artner T, Turnes BL, Serhan N, Oliveira T, Gail LM, Stejskal K, Channon KM, Köcher T, Stary G, Klang V, Gaudenzio N, Knapp S, Woolf CJ, Penninger JM, Cronin SJF. Starkl P, et al. bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525378. doi: 10.1101/2023.01.24.525378. bioRxiv. 2023. PMID: 37293068 Free PMC article. Preprint.
Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis.
Bülck C, Nyström EEL, Koudelka T, Mannbar-Frahm M, Andresen G, Radhouani M, Tran F, Scharfenberg F, Schrell F, Armbrust F, Dahlke E, Zhao B, Vervaeke A, Theilig F, Rosenstiel P, Starkl P, Rosshart SP, Fickenscher H, Tholey A, Hansson GC, Becker-Pauly C. Bülck C, et al. Among authors: starkl p. Sci Adv. 2023 Mar 31;9(13):eadf4055. doi: 10.1126/sciadv.adf4055. Epub 2023 Mar 31. Sci Adv. 2023. PMID: 37000885 Free PMC article.
Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling.
Zahalka S, Starkl P, Watzenboeck ML, Farhat A, Radhouani M, Deckert F, Hladik A, Lakovits K, Oberndorfer F, Lassnig C, Strobl B, Klavins K, Matsushita M, Sanin DE, Grzes KM, Pearce EJ, Gorki AD, Knapp S. Zahalka S, et al. Among authors: starkl p. Mucosal Immunol. 2022 May;15(5):896-907. doi: 10.1038/s41385-022-00528-5. Epub 2022 Jul 18. Mucosal Immunol. 2022. PMID: 35856089 Free PMC article.
Development of an aerosol intervention for COVID-19 disease: Tolerability of soluble ACE2 (APN01) administered via nebulizer.
Shoemaker RH, Panettieri RA Jr, Libutti SK, Hochster HS, Watts NR, Wingfield PT, Starkl P, Pimenov L, Gawish R, Hladik A, Knapp S, Boring D, White JM, Lawrence Q, Boone J, Marshall JD, Matthews RL, Cholewa BD, Richig JW, Chen BT, McCormick DL, Gugensberger R, Höller S, Penninger JM, Wirnsberger G. Shoemaker RH, et al. Among authors: starkl p. PLoS One. 2022 Jul 11;17(7):e0271066. doi: 10.1371/journal.pone.0271066. eCollection 2022. PLoS One. 2022. PMID: 35816490 Free PMC article.
ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology.
Gawish R, Starkl P, Pimenov L, Hladik A, Lakovits K, Oberndorfer F, Cronin SJ, Ohradanova-Repic A, Wirnsberger G, Agerer B, Endler L, Capraz T, Perthold JW, Cikes D, Koglgruber R, Hagelkruys A, Montserrat N, Mirazimi A, Boon L, Stockinger H, Bergthaler A, Oostenbrink C, Penninger JM, Knapp S. Gawish R, et al. Among authors: starkl p. Elife. 2022 Jan 13;11:e74623. doi: 10.7554/eLife.74623. Elife. 2022. PMID: 35023830 Free PMC article.
Development of a novel, pan-variant aerosol intervention for COVID-19.
Shoemaker RH, Panettieri RA Jr, Libutti SK, Hochster HS, Watts NR, Wingfield PT, Starkl P, Pimenov L, Gawish R, Hladik A, Knapp S, Boring D, White JM, Lawrence Q, Boone J, Marshall JD, Matthews RL, Cholewa BD, Richig JW, Chen BT, McCormick DL, Gugensberger R, Höller S, Penninger JM, Wirnsberger G. Shoemaker RH, et al. Among authors: starkl p. bioRxiv [Preprint]. 2021 Sep 20:2021.09.14.459961. doi: 10.1101/2021.09.14.459961. bioRxiv. 2021. PMID: 34545364 Free PMC article. Updated. Preprint.
Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome.
Stackowicz J, Gaudenzio N, Serhan N, Conde E, Godon O, Marichal T, Starkl P, Balbino B, Roers A, Bruhns P, Jönsson F, Moguelet P, Georgin-Lavialle S, Broderick L, Hoffman HM, Galli SJ, Reber LL. Stackowicz J, et al. Among authors: starkl p. J Exp Med. 2021 Oct 4;218(10):e20201466. doi: 10.1084/jem.20201466. Epub 2021 Sep 3. J Exp Med. 2021. PMID: 34477811 Free PMC article.
Multi-omics profiling predicts allograft function after lung transplantation.
Watzenboeck ML, Gorki AD, Quattrone F, Gawish R, Schwarz S, Lambers C, Jaksch P, Lakovits K, Zahalka S, Rahimi N, Starkl P, Symmank D, Artner T, Pattaroni C, Fortelny N, Klavins K, Frommlet F, Marsland BJ, Hoetzenecker K, Widder S, Knapp S. Watzenboeck ML, et al. Among authors: starkl p. Eur Respir J. 2022 Feb 3;59(2):2003292. doi: 10.1183/13993003.03292-2020. Print 2022 Feb. Eur Respir J. 2022. PMID: 34244315 Free article.
Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner.
Watzenboeck ML, Drobits B, Zahalka S, Gorki AD, Farhat A, Quattrone F, Hladik A, Lakovits K, Richard GM, Lederer T, Strobl B, Versteeg GA, Boon L, Starkl P, Knapp S. Watzenboeck ML, et al. Among authors: starkl p. PLoS Pathog. 2021 Apr 27;17(4):e1009487. doi: 10.1371/journal.ppat.1009487. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33905460 Free PMC article.
57 results