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A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans.
Caballero-Camino FJ, Rodrigues PM, Wångsell F, Agirre-Lizaso A, Olaizola P, Izquierdo-Sanchez L, Perugorria MJ, Bujanda L, Angelin B, Straniero S, Wallebäck A, Starke I, Gillberg PG, Strängberg E, Bonn B, Mattsson JP, Madsen MR, Hansen HH, Lindström E, Åkerblad P, Banales JM. Caballero-Camino FJ, et al. Among authors: starke i. Hepatology. 2023 Sep 1;78(3):709-726. doi: 10.1097/HEP.0000000000000376. Epub 2023 Apr 1. Hepatology. 2023. PMID: 36999529 Free PMC article.
Mechanism and impact of catecholamine conversion by Vibrio cholerae.
Toulouse C, Schmucker S, Metesch K, Pfannstiel J, Michel B, Starke I, Möller HM, Stefanski V, Steuber J. Toulouse C, et al. Among authors: starke i. Biochim Biophys Acta Bioenerg. 2019 Jun 1;1860(6):478-487. doi: 10.1016/j.bbabio.2019.04.003. Epub 2019 Apr 12. Biochim Biophys Acta Bioenerg. 2019. PMID: 30986392 Free article.
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.
Knerr L, Giordanetto F, Nordberg P, Pettersen D, Selmi N, Beisel HG, de la Motte H, Olsson T, Perkins TDJ, Herslöf M, Månsson Å, Dahlström M, Starke I, Broddefalk J, Saarinen G, Klingegård F, Hurt-Camejo E, Rosengren B, Brengdahl J, Jansen F, Rohman M, Sandmark J, Hallberg K, Åkerud T, Roth RG, Ahlqvist M. Knerr L, et al. Among authors: starke i. ACS Med Chem Lett. 2018 Jun 23;9(7):594-599. doi: 10.1021/acsmedchemlett.7b00505. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034585 Free PMC article.
Discovery of AZD2716: A Novel Secreted Phospholipase A2 (sPLA2) Inhibitor for the Treatment of Coronary Artery Disease.
Giordanetto F, Pettersen D, Starke I, Nordberg P, Dahlström M, Knerr L, Selmi N, Rosengren B, Larsson LO, Sandmark J, Castaldo M, Dekker N, Karlsson U, Hurt-Camejo E. Giordanetto F, et al. Among authors: starke i. ACS Med Chem Lett. 2016 Aug 9;7(10):884-889. doi: 10.1021/acsmedchemlett.6b00188. eCollection 2016 Oct 13. ACS Med Chem Lett. 2016. PMID: 27774123 Free PMC article.
63 results