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Cryo-EM in drug discovery: achievements, limitations and prospects.
Renaud JP, Chari A, Ciferri C, Liu WT, Rémigy HW, Stark H, Wiesmann C. Renaud JP, et al. Among authors: stark h. Nat Rev Drug Discov. 2018 Jul;17(7):471-492. doi: 10.1038/nrd.2018.77. Epub 2018 Jun 8. Nat Rev Drug Discov. 2018. PMID: 29880918 Review.
GraFix: sample preparation for single-particle electron cryomicroscopy.
Kastner B, Fischer N, Golas MM, Sander B, Dube P, Boehringer D, Hartmuth K, Deckert J, Hauer F, Wolf E, Uchtenhagen H, Urlaub H, Herzog F, Peters JM, Poerschke D, Lührmann R, Stark H. Kastner B, et al. Among authors: stark h. Nat Methods. 2008 Jan;5(1):53-5. doi: 10.1038/nmeth1139. Epub 2007 Dec 23. Nat Methods. 2008. PMID: 18157137
Structural basis of assembly chaperone- mediated snRNP formation.
Grimm C, Chari A, Pelz JP, Kuper J, Kisker C, Diederichs K, Stark H, Schindelin H, Fischer U. Grimm C, et al. Among authors: stark h. Mol Cell. 2013 Feb 21;49(4):692-703. doi: 10.1016/j.molcel.2012.12.009. Epub 2013 Jan 17. Mol Cell. 2013. PMID: 23333303 Free article.
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space.
Chari A, Haselbach D, Kirves JM, Ohmer J, Paknia E, Fischer N, Ganichkin O, Möller V, Frye JJ, Petzold G, Jarvis M, Tietzel M, Grimm C, Peters JM, Schulman BA, Tittmann K, Markl J, Fischer U, Stark H. Chari A, et al. Among authors: stark h. Nat Methods. 2015 Sep;12(9):859-65. doi: 10.1038/nmeth.3493. Epub 2015 Aug 3. Nat Methods. 2015. PMID: 26237227 Free PMC article.
Molecular architecture of the human U4/U6.U5 tri-snRNP.
Agafonov DE, Kastner B, Dybkov O, Hofele RV, Liu WT, Urlaub H, Lührmann R, Stark H. Agafonov DE, et al. Among authors: stark h. Science. 2016 Mar 25;351(6280):1416-20. doi: 10.1126/science.aad2085. Epub 2016 Feb 18. Science. 2016. PMID: 26912367
1,174 results