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Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.
Muik A, Garralda E, Altintas I, Gieseke F, Geva R, Ben-Ami E, Maurice-Dror C, Calvo E, LoRusso PM, Alonso G, Rodriguez-Ruiz ME, Schoedel KB, Blum JM, Sänger B, Salcedo TW, Burm SM, Stanganello E, Verzijl D, Vascotto F, Sette A, Quinkhardt J, Plantinga TS, Toker A, van den Brink EN, Fereshteh M, Diken M, Satijn D, Kreiter S, Breij ECW, Bajaj G, Lagkadinou E, Sasser K, Türeci Ö, Forssmann U, Ahmadi T, Şahin U, Jure-Kunkel M, Melero I. Muik A, et al. Among authors: stanganello e. Cancer Discov. 2022 May 2;12(5):1248-1265. doi: 10.1158/2159-8290.CD-21-1345. Cancer Discov. 2022. PMID: 35176764 Free PMC article. Clinical Trial.
DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
Muik A, Adams 3rd HC, Gieseke F, Altintas I, Schoedel KB, Blum JM, Sänger B, Burm SM, Stanganello E, Verzijl D, Spires VM, Vascotto F, Toker A, Quinkhardt J, Fereshteh M, Diken M, Satijn DPE, Kreiter S, Ahmadi T, Breij ECW, Türeci Ö, Sasser K, Sahin U, Jure-Kunkel M. Muik A, et al. Among authors: stanganello e. J Immunother Cancer. 2022 Jun;10(6):e004322. doi: 10.1136/jitc-2021-004322. J Immunother Cancer. 2022. PMID: 35688554 Free PMC article.
Local radiotherapy and E7 RNA-LPX vaccination show enhanced therapeutic efficacy in preclinical models of HPV16+ cancer.
Salomon N, Selmi A, Grunwitz C, Kong A, Stanganello E, Neumaier J, Petschenka J, Diken M, Kreiter S, Türeci Ö, Sahin U, Vascotto F. Salomon N, et al. Among authors: stanganello e. Cancer Immunol Immunother. 2022 Aug;71(8):1975-1988. doi: 10.1007/s00262-021-03134-9. Epub 2021 Dec 31. Cancer Immunol Immunother. 2022. PMID: 34971406 Free PMC article.
Tumor-expressed factor VII is associated with survival and regulates tumor progression in breast cancer.
Kroone C, Tieken C, Kocatürk B, Paauwe M, Blok EJ, Ünlü B, van den Berg YW, Stanganello E, Kapteijn MY, Swier N, Zhang X, Duits DEM, Lin Y, Oostenbrink LVE, van den Akker RFP, Mosnier LO, Hawinkels LJ, van Vlijmen BJM, Ruf W, Kuppen PJ, Cannegieter SC, Buijs JT, Versteeg HH. Kroone C, et al. Among authors: stanganello e. Blood Adv. 2023 Jun 13;7(11):2388-2400. doi: 10.1182/bloodadvances.2022008455. Blood Adv. 2023. PMID: 36920782 Free PMC article.
Wnt Signaling Directs Neuronal Polarity and Axonal Growth.
Stanganello E, Zahavi EE, Burute M, Smits J, Jordens I, Maurice MM, Kapitein LC, Hoogenraad CC. Stanganello E, et al. iScience. 2019 Mar 29;13:318-327. doi: 10.1016/j.isci.2019.02.029. Epub 2019 Mar 2. iScience. 2019. PMID: 30878878 Free PMC article.
Role of cytonemes in Wnt transport.
Stanganello E, Scholpp S. Stanganello E, et al. J Cell Sci. 2016 Feb 15;129(4):665-72. doi: 10.1242/jcs.182469. Epub 2016 Jan 28. J Cell Sci. 2016. PMID: 26823607 Review.