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Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: staels b. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.
Studies towards the conception of new selective PPARbeta/delta ligands.
Basséne CE, Suzenet F, Hennuyer N, Staels B, Caignard DH, Dacquet C, Renard P, Guillaumet G. Basséne CE, et al. Among authors: staels b. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4528-32. doi: 10.1016/j.bmcl.2006.06.028. Epub 2006 Jun 23. Bioorg Med Chem Lett. 2006. PMID: 16797985
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.
Michalik L, Auwerx J, Berger JP, Chatterjee VK, Glass CK, Gonzalez FJ, Grimaldi PA, Kadowaki T, Lazar MA, O'Rahilly S, Palmer CN, Plutzky J, Reddy JK, Spiegelman BM, Staels B, Wahli W. Michalik L, et al. Among authors: staels b. Pharmacol Rev. 2006 Dec;58(4):726-41. doi: 10.1124/pr.58.4.5. Pharmacol Rev. 2006. PMID: 17132851 Review.
S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.
Carmona MC, Louche K, Lefebvre B, Pilon A, Hennuyer N, Audinot-Bouchez V, Fievet C, Torpier G, Formstecher P, Renard P, Lefebvre P, Dacquet C, Staels B, Casteilla L, Pénicaud L; Consortium of the French Ministry of Research and Technology. Carmona MC, et al. Among authors: staels b. Diabetes. 2007 Nov;56(11):2797-808. doi: 10.2337/db06-1734. Epub 2007 Aug 17. Diabetes. 2007. PMID: 17704298
792 results