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Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release.
Szot C, Saha S, Zhang XM, Zhu Z, Hilton MB, Morris K, Seaman S, Dunleavey JM, Hsu KS, Yu GJ, Morris H, Swing DA, Haines DC, Wang Y, Hwang J, Feng Y, Welsch D, DeCrescenzo G, Chaudhary A, Zudaire E, Dimitrov DS, St Croix B. Szot C, et al. Among authors: st croix b. J Clin Invest. 2018 Jul 2;128(7):2927-2943. doi: 10.1172/JCI120481. Epub 2018 Jun 4. J Clin Invest. 2018. PMID: 29863500 Free PMC article.
Cancer cell survival depends on collagen uptake into tumor-associated stroma.
Hsu KS, Dunleavey JM, Szot C, Yang L, Hilton MB, Morris K, Seaman S, Feng Y, Lutz EM, Koogle R, Tomassoni-Ardori F, Saha S, Zhang XM, Zudaire E, Bajgain P, Rose J, Zhu Z, Dimitrov DS, Cuttitta F, Emenaker NJ, Tessarollo L, St Croix B. Hsu KS, et al. Among authors: st croix b. Nat Commun. 2022 Nov 18;13(1):7078. doi: 10.1038/s41467-022-34643-5. Nat Commun. 2022. PMID: 36400786 Free PMC article.
Immuno-PET imaging of tumor endothelial marker 8 (TEM8).
Kuo F, Histed S, Xu B, Bhadrasetty V, Szajek LP, Williams MR, Wong K, Wu H, Lane K, Coble V, Vasalatiy O, Griffiths GL, Paik CH, Elbuluk O, Szot C, Chaudhary A, St Croix B, Choyke P, Jagoda EM. Kuo F, et al. Among authors: st croix b. Mol Pharm. 2014 Nov 3;11(11):3996-4006. doi: 10.1021/mp500056d. Epub 2014 Jul 11. Mol Pharm. 2014. PMID: 24984190 Free PMC article.
Host-derived tumor endothelial marker 8 promotes the growth of melanoma.
Cullen M, Seaman S, Chaudhary A, Yang MY, Hilton MB, Logsdon D, Haines DC, Tessarollo L, St Croix B. Cullen M, et al. Among authors: st croix b. Cancer Res. 2009 Aug 1;69(15):6021-6. doi: 10.1158/0008-5472.CAN-09-1086. Epub 2009 Jul 21. Cancer Res. 2009. PMID: 19622764 Free PMC article.
Selective blockade of tumor angiogenesis.
Chaudhary A, St Croix B. Chaudhary A, et al. Among authors: st croix b. Cell Cycle. 2012 Jun 15;11(12):2253-9. doi: 10.4161/cc.20374. Epub 2012 Jun 15. Cell Cycle. 2012. PMID: 22617387 Free PMC article.
55 results