Stępniewski T - Search Results

1

Oxazoline scaffold in synthesis of benzosiloxaboroles and related ring-expanded heterocycles: diverse reactivity, structural peculiarities and antimicrobial activity.

Krajewska J, Nowicki K, Durka K, Marek-Urban PH, Wińska P, Stępniewski T, Woźniak K, Laudy AE, Luliński S. Krajewska J, et al. Among authors: stepniewski t. RSC Adv. 2022 Aug 16;12(36):23099-23117. doi: 10.1039/d2ra03910a. eCollection 2022 Aug 16. RSC Adv. 2022. PMID: 36090419 Free PMC article.

2

Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling.

Dwivedi-Agnihotri H, Chaturvedi M, Baidya M, Stepniewski TM, Pandey S, Maharana J, Srivastava A, Caengprasath N, Hanyaloglu AC, Selent J, Shukla AK. Dwivedi-Agnihotri H, et al. Sci Adv. 2020 Sep 11;6(37):eabb8368. doi: 10.1126/sciadv.abb8368. Print 2020 Sep. Sci Adv. 2020. PMID: 32917711 Free PMC article.

3

A molecular sensor for cholesterol in the human serotonin_1A receptor.

Kumar GA, Sarkar P, Stepniewski TM, Jafurulla M, Singh SP, Selent J, Chattopadhyay A. Kumar GA, et al. Sci Adv. 2021 Jul 23;7(30):eabh2922. doi: 10.1126/sciadv.abh2922. Print 2021 Jul. Sci Adv. 2021. PMID: 34301606 Free PMC article.

4

How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs.

Torrens-Fontanals M, Stepniewski TM, Aranda-García D, Morales-Pastor A, Medel-Lacruz B, Selent J. Torrens-Fontanals M, et al. Int J Mol Sci. 2020 Aug 18;21(16):5933. doi: 10.3390/ijms21165933. Int J Mol Sci. 2020. PMID: 32824756 Free PMC article. Review.

5

Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists.

Stepniewski TM, Torrens-Fontanals M, Rodríguez-Espigares I, Giorgino T, Primdahl KG, Vik A, Stenstrøm Y, Selent J, Hansen TV. Stepniewski TM, et al. Bioorg Med Chem. 2018 Jul 23;26(12):3580-3587. doi: 10.1016/j.bmc.2018.05.036. Epub 2018 May 23. Bioorg Med Chem. 2018. PMID: 29866479

6

Palmitoylation of cysteine 415 of CB₁ receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1.

Oddi S, Stepniewski TM, Totaro A, Selent J, Scipioni L, Dufrusine B, Fezza F, Dainese E, Maccarrone M. Oddi S, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):523-532. doi: 10.1016/j.bbalip.2017.02.004. Epub 2017 Feb 12. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28215712

7

Role of palmitoylation of cysteine 415 in functional coupling CB₁ receptor to Gα_i2 protein.

Oddi S, Totaro A, Scipioni L, Dufrusine B, Stepniewski TM, Selent J, Maccarrone M, Dainese E. Oddi S, et al. Biotechnol Appl Biochem. 2018 Jan;65(1):16-20. doi: 10.1002/bab.1575. Epub 2017 Aug 15. Biotechnol Appl Biochem. 2018. PMID: 28722168

8

Development of Fluorescent Probes that Target Serotonin 5-HT_2B Receptors.

Azuaje J, López P, Iglesias A, de la Fuente RA, Pérez-Rubio JM, García D, Stępniewski TM, García-Mera X, Brea JM, Selent J, Pérez D, Castro M, Loza MI, Sotelo E. Azuaje J, et al. Sci Rep. 2017 Sep 7;7(1):10765. doi: 10.1038/s41598-017-11370-2. Sci Rep. 2017. PMID: 28883627 Free PMC article.

9

Challenges and Opportunities in Drug Discovery of Biased Ligands.

Rodríguez-Espigares I, Kaczor AA, Stepniewski TM, Selent J. Rodríguez-Espigares I, et al. Methods Mol Biol. 2018;1705:321-334. doi: 10.1007/978-1-4939-7465-8_14. Methods Mol Biol. 2018. PMID: 29188569 Review.

10

Protein-Protein Docking in Drug Design and Discovery.

Kaczor AA, Bartuzi D, Stępniewski TM, Matosiuk D, Selent J. Kaczor AA, et al. Methods Mol Biol. 2018;1762:285-305. doi: 10.1007/978-1-4939-7756-7_15. Methods Mol Biol. 2018. PMID: 29594778

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