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The hallmarks of fibroblast ageing.
Tigges J, Krutmann J, Fritsche E, Haendeler J, Schaal H, Fischer JW, Kalfalah F, Reinke H, Reifenberger G, Stühler K, Ventura N, Gundermann S, Boukamp P, Boege F. Tigges J, et al. Among authors: stuhler k. Mech Ageing Dev. 2014 Jun;138:26-44. doi: 10.1016/j.mad.2014.03.004. Epub 2014 Mar 29. Mech Ageing Dev. 2014. PMID: 24686308 Review.
Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts.
Waldera-Lupa DM, Kalfalah F, Florea AM, Sass S, Kruse F, Rieder V, Tigges J, Fritsche E, Krutmann J, Busch H, Boerries M, Meyer HE, Boege F, Theis F, Reifenberger G, Stühler K. Waldera-Lupa DM, et al. Among authors: stuhler k. Aging (Albany NY). 2014 Oct;6(10):856-78. doi: 10.18632/aging.100698. Aging (Albany NY). 2014. PMID: 25411231 Free PMC article.
Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.
Waldera Lupa DM, Kalfalah F, Safferling K, Boukamp P, Poschmann G, Volpi E, Götz-Rösch C, Bernerd F, Haag L, Huebenthal U, Fritsche E, Boege F, Grabe N, Tigges J, Stühler K, Krutmann J. Waldera Lupa DM, et al. Among authors: stuhler k. J Invest Dermatol. 2015 Aug;135(8):1954-1968. doi: 10.1038/jid.2015.120. Epub 2015 Mar 27. J Invest Dermatol. 2015. PMID: 25815425 Free article.
MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4.
Lang A, Grether-Beck S, Singh M, Kuck F, Jakob S, Kefalas A, Altinoluk-Hambüchen S, Graffmann N, Schneider M, Lindecke A, Brenden H, Felsner I, Ezzahoini H, Marini A, Weinhold S, Vierkötter A, Tigges J, Schmidt S, Stühler K, Köhrer K, Uhrberg M, Haendeler J, Krutmann J, Piekorz RP. Lang A, et al. Among authors: stuhler k. Aging (Albany NY). 2016 Mar;8(3):484-505. doi: 10.18632/aging.100905. Aging (Albany NY). 2016. PMID: 26959556 Free PMC article.
Succession of splicing regulatory elements determines cryptic 5΄ss functionality.
Brillen AL, Schöneweis K, Walotka L, Hartmann L, Müller L, Ptok J, Kaisers W, Poschmann G, Stühler K, Buratti E, Theiss S, Schaal H. Brillen AL, et al. Among authors: stuhler k. Nucleic Acids Res. 2017 Apr 20;45(7):4202-4216. doi: 10.1093/nar/gkw1317. Nucleic Acids Res. 2017. PMID: 28039323 Free PMC article.
SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy.
Lang A, Anand R, Altinoluk-Hambüchen S, Ezzahoini H, Stefanski A, Iram A, Bergmann L, Urbach J, Böhler P, Hänsel J, Franke M, Stühler K, Krutmann J, Scheller J, Stork B, Reichert AS, Piekorz RP. Lang A, et al. Among authors: stuhler k. Aging (Albany NY). 2017 Oct 29;9(10):2163-2189. doi: 10.18632/aging.101307. Aging (Albany NY). 2017. PMID: 29081403 Free PMC article.
169 results