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Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization.
Commun Biol. 2021 Jun 21;4(1):762. doi: 10.1038/s42003-021-02253-4.
Commun Biol. 2021.
PMID: 34155320
Free PMC article.
Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action.
Kast F, Schwill M, Stüber JC, Pfundstein S, Nagy-Davidescu G, Rodríguez JMM, Seehusen F, Richter CP, Honegger A, Hartmann KP, Weber TG, Kroener F, Ernst P, Piehler J, Plückthun A.
Kast F, et al. Among authors: stuber jc.
Nat Commun. 2021 Jun 18;12(1):3790. doi: 10.1038/s41467-021-23948-6.
Nat Commun. 2021.
PMID: 34145240
Free PMC article.
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Rigidity of the extracellular part of HER2: Evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions.
Jost C, Stüber JC, Honegger A, Wu Y, Batyuk A, Plückthun A.
Jost C, et al. Among authors: stuber jc.
Protein Sci. 2017 Sep;26(9):1796-1806. doi: 10.1002/pro.3216. Epub 2017 Jul 5.
Protein Sci. 2017.
PMID: 28639341
Free PMC article.
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Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.
Andres F, Iamele L, Meyer T, Stüber JC, Kast F, Gherardi E, Niemann HH, Plückthun A.
Andres F, et al. Among authors: stuber jc.
J Mol Biol. 2019 May 3;431(10):2020-2039. doi: 10.1016/j.jmb.2019.03.024. Epub 2019 Mar 28.
J Mol Biol. 2019.
PMID: 30930049
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High-Throughput Quantification of Surface Protein Internalization and Degradation.
Stüber JC, Kast F, Plückthun A.
Stüber JC, et al.
ACS Chem Biol. 2019 Jun 21;14(6):1154-1163. doi: 10.1021/acschembio.9b00016. Epub 2019 May 14.
ACS Chem Biol. 2019.
PMID: 31050891
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Labeling surface proteins with high specificity: Intrinsic limitations of phosphopantetheinyl transferase systems.
Stüber JC, Plückthun A.
Stüber JC, et al.
PLoS One. 2019 Dec 19;14(12):e0226579. doi: 10.1371/journal.pone.0226579. eCollection 2019.
PLoS One. 2019.
PMID: 31856184
Free PMC article.
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Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells.
König I, Zarrine-Afsar A, Aznauryan M, Soranno A, Wunderlich B, Dingfelder F, Stüber JC, Plückthun A, Nettels D, Schuler B.
König I, et al. Among authors: stuber jc.
Nat Methods. 2015 Aug;12(8):773-9. doi: 10.1038/nmeth.3475. Epub 2015 Jul 6.
Nat Methods. 2015.
PMID: 26147918
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Design and applications of a clamp for Green Fluorescent Protein with picomolar affinity.
Hansen S, Stüber JC, Ernst P, Koch A, Bojar D, Batyuk A, Plückthun A.
Hansen S, et al. Among authors: stuber jc.
Sci Rep. 2017 Nov 24;7(1):16292. doi: 10.1038/s41598-017-15711-z.
Sci Rep. 2017.
PMID: 29176615
Free PMC article.
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