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A Phase 1/2 Study of the Oral Janus Kinase 1 Inhibitors INCB052793 and Itacitinib Alone or in Combination With Standard Therapies for Advanced Hematologic Malignancies.
Zeidan AM, Cook RJ, Bordoni R, Berenson JR, Edenfield WJ, Mohan S, Zhou G, Asatiani E, Srinivas N, Savona MR. Zeidan AM, et al. Among authors: srinivas n. Clin Lymphoma Myeloma Leuk. 2022 Jul;22(7):523-534. doi: 10.1016/j.clml.2022.01.012. Epub 2022 Jan 20. Clin Lymphoma Myeloma Leuk. 2022. PMID: 35260349 Clinical Trial.
A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease.
Schroeder MA, Khoury HJ, Jagasia M, Ali H, Schiller GJ, Staser K, Choi J, Gehrs L, Arbushites MC, Yan Y, Langmuir P, Srinivas N, Pratta M, Perales MA, Chen YB, Meyers G, DiPersio JF. Schroeder MA, et al. Among authors: srinivas n. Blood Adv. 2020 Apr 28;4(8):1656-1669. doi: 10.1182/bloodadvances.2019001043. Blood Adv. 2020. PMID: 32324888 Free PMC article. Clinical Trial.
Leveraging innovative technology to generate drug response phenotypes for the advancement of biomarker-driven precision dosing.
Oni-Orisan A, Srinivas N, Mehta K, Das JL, Nguyen TT, Tison GH, Bauer SR, Burian M, Funk RS, Graham RA; Biomarkers and Translational Tools Community Working Group of the American Society for Clinical Pharmacology and Therapeutics. Oni-Orisan A, et al. Among authors: srinivas n. Clin Transl Sci. 2021 May;14(3):784-790. doi: 10.1111/cts.12973. Epub 2021 Feb 12. Clin Transl Sci. 2021. PMID: 33421282 Free PMC article.
Predicting Efavirenz Concentrations in the Brain Tissue of HIV-Infected Individuals and Exploring their Relationship to Neurocognitive Impairment.
Srinivas N, Joseph SB, Robertson K, Kincer LP, Menezes P, Adamson L, Schauer AP, Blake KH, White N, Sykes C, Luciw P, Eron JJ, Forrest A, Price RW, Spudich S, Swanstrom R, Kashuba ADM. Srinivas N, et al. Clin Transl Sci. 2019 May;12(3):302-311. doi: 10.1111/cts.12620. Epub 2019 Feb 27. Clin Transl Sci. 2019. PMID: 30675981 Free PMC article. Clinical Trial.
Pharmacokinetics of antiretrovirals in mucosal tissue.
Cottrell ML, Srinivas N, Kashuba AD. Cottrell ML, et al. Among authors: srinivas n. Expert Opin Drug Metab Toxicol. 2015 Jun;11(6):893-905. doi: 10.1517/17425255.2015.1027682. Epub 2015 Mar 22. Expert Opin Drug Metab Toxicol. 2015. PMID: 25797064 Free PMC article. Review.
Multimodal analysis of drug transporter expression in gastrointestinal tissue.
Thompson CG, Fallon JK, Mathews M, Charlins P, Remling-Mulder L, Kovarova M, Adamson L, Srinivas N, Schauer A, Sykes C, Luciw P, Garcia JV, Akkina R, Smith PC, Kashuba ADM. Thompson CG, et al. Among authors: srinivas n. AIDS. 2017 Jul 31;31(12):1669-1678. doi: 10.1097/QAD.0000000000001554. AIDS. 2017. PMID: 28590331 Free PMC article.
Antiretroviral Penetration across Three Preclinical Animal Models and Humans in Eight Putative HIV Viral Reservoirs.
Devanathan AS, Pirone JR, Akkina R, Remling-Mulder L, Luciw P, Adamson L, Garcia JV, Kovarova M, White NR, Schauer AP, Blake K, Sykes C, Burgunder EM, Srinivas N, Rosen EP, Kashuba ADM. Devanathan AS, et al. Among authors: srinivas n. Antimicrob Agents Chemother. 2019 Dec 20;64(1):e01639-19. doi: 10.1128/AAC.01639-19. Print 2019 Dec 20. Antimicrob Agents Chemother. 2019. PMID: 31611355 Free PMC article.
480 results