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The plant pathogen enzyme AldC is a long-chain aliphatic aldehyde dehydrogenase.
Lee SG, Harline K, Abar O, Akadri SO, Bastian AG, Chen HS, Duan M, Focht CM, Groziak AR, Kao J, Kottapalli JS, Leong MC, Lin JJ, Liu R, Luo JE, Meyer CM, Mo AF, Pahng SH, Penna V, Raciti CD, Srinath A, Sudhakar S, Tang JD, Cox BR, Holland CK, Cascella B, Cruz W, McClerkin SA, Kunkel BN, Jez JM. Lee SG, et al. Among authors: srinath a. J Biol Chem. 2020 Oct 2;295(40):13914-13926. doi: 10.1074/jbc.RA120.014747. Epub 2020 Aug 12. J Biol Chem. 2020. PMID: 32796031 Free PMC article.
Rapamycin in Cerebral Cavernous Malformations: What Doses to Test in Mice and Humans.
Hagan MJ, Shenkar R, Srinath A, Romanos SG, Stadnik A, Kahn ML, Marchuk DA, Girard R, Awad IA. Hagan MJ, et al. Among authors: srinath a. ACS Pharmacol Transl Sci. 2022 Apr 25;5(5):266-277. doi: 10.1021/acsptsci.2c00006. eCollection 2022 May 13. ACS Pharmacol Transl Sci. 2022. PMID: 35592432 Free PMC article. Review.
Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.
Koskimäki J, Zhang D, Li Y, Saadat L, Moore T, Lightle R, Polster SP, Carrión-Penagos J, Lyne SB, Zeineddine HA, Shi C, Shenkar R, Romanos S, Avner K, Srinath A, Shen L, Detter MR, Snellings D, Cao Y, Lopez-Ramirez MA, Fonseca G, Tang AT, Faber P, Andrade J, Ginsberg M, Kahn ML, Marchuk DA, Girard R, Awad IA. Koskimäki J, et al. Among authors: srinath a. Acta Neuropathol Commun. 2019 Aug 19;7(1):132. doi: 10.1186/s40478-019-0789-0. Acta Neuropathol Commun. 2019. PMID: 31426861 Free PMC article.
Cerebral Cavernous Malformation: From Mechanism to Therapy.
Snellings DA, Hong CC, Ren AA, Lopez-Ramirez MA, Girard R, Srinath A, Marchuk DA, Ginsberg MH, Awad IA, Kahn ML. Snellings DA, et al. Among authors: srinath a. Circ Res. 2021 Jun 25;129(1):195-215. doi: 10.1161/CIRCRESAHA.121.318174. Epub 2021 Jun 24. Circ Res. 2021. PMID: 34166073 Free PMC article. Review.
Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions.
Magid-Bernstein J, Girard R, Polster S, Srinath A, Romanos S, Awad IA, Sansing LH. Magid-Bernstein J, et al. Among authors: srinath a. Circ Res. 2022 Apr 15;130(8):1204-1229. doi: 10.1161/CIRCRESAHA.121.319949. Epub 2022 Apr 14. Circ Res. 2022. PMID: 35420918 Free PMC article. Review.
Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease.
Romanos SG, Srinath A, Li Y, Xie B, Chen C, Li Y, Moore T, Bi D, Sone JY, Lightle R, Hobson N, Zhang D, Koskimäki J, Shen L, McCurdy S, Lai CC, Stadnik A, Piedad K, Carrión-Penagos J, Shkoukani A, Snellings D, Shenkar R, Sulakhe D, Ji Y, Lopez-Ramirez MA, Kahn ML, Marchuk DA, Ginsberg MH, Girard R, Awad IA. Romanos SG, et al. Among authors: srinath a. Transl Stroke Res. 2023 Aug;14(4):513-529. doi: 10.1007/s12975-022-01050-3. Epub 2022 Jun 17. Transl Stroke Res. 2023. PMID: 35715588
Common transcriptome, plasma molecules, and imaging signatures in the aging brain and a Mendelian neurovascular disease, cerebral cavernous malformation.
Koskimäki J, Polster SP, Li Y, Romanos S, Srinath A, Zhang D, Carrión-Penagos J, Lightle R, Moore T, Lyne SB, Stadnik A, Piedad K, Cao Y, Shenkar R, Dimov AV, Hobson N, Christoforidis GA, Carroll T, Girard R, Awad IA. Koskimäki J, et al. Among authors: srinath a. Geroscience. 2020 Oct;42(5):1351-1363. doi: 10.1007/s11357-020-00201-4. Epub 2020 Jun 17. Geroscience. 2020. PMID: 32556941 Free PMC article.
A Roadmap for Developing Plasma Diagnostic and Prognostic Biomarkers of Cerebral Cavernous Angioma With Symptomatic Hemorrhage (CASH).
Girard R, Li Y, Stadnik A, Shenkar R, Hobson N, Romanos S, Srinath A, Moore T, Lightle R, Shkoukani A, Akers A, Carroll T, Christoforidis GA, Koenig JI, Lee C, Piedad K, Greenberg SM, Kim H, Flemming KD, Ji Y, Awad IA. Girard R, et al. Among authors: srinath a. Neurosurgery. 2021 Feb 16;88(3):686-697. doi: 10.1093/neuros/nyaa478. Neurosurgery. 2021. PMID: 33469662 Free PMC article.
79 results