Srilatha Sakamuru - Search Results

Year	Number of Results
2009	2
2010	4
2011	4
2012	2
2013	3
2014	3
2015	3
2016	7
2017	6
2018	4
2019	6
2020	3
2021	8
2022	7
2023	3
2024	1

1

High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.

Lynch C, Sakamuru S, Ooka M, Huang R, Klumpp-Thomas C, Shinn P, Gerhold D, Rossoshek A, Michael S, Casey W, Santillo MF, Fitzpatrick S, Thomas RS, Simeonov A, Xia M. Lynch C, et al. Among authors: sakamuru s. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:191-209. doi: 10.1146/annurev-pharmtox-112122-104310. Epub 2023 Jul 28. Annu Rev Pharmacol Toxicol. 2024. PMID: 37506331 Free PMC article. Review.

2

Identification of Potent and Selective Acetylcholinesterase/Butyrylcholinesterase Inhibitors by Virtual Screening.

Xu T, Li S, Li AJ, Zhao J, Sakamuru S, Huang W, Xia M, Huang R. Xu T, et al. Among authors: sakamuru s. J Chem Inf Model. 2023 Apr 24;63(8):2321-2330. doi: 10.1021/acs.jcim.3c00230. Epub 2023 Apr 3. J Chem Inf Model. 2023. PMID: 37011147 Free PMC article.

3

Predictive Models for Human Cytochrome P450 3A7 Selective Inhibitors and Substrates.

Xu T, Kabir M, Sakamuru S, Shah P, Padilha EC, Ngan DK, Xia M, Xu X, Simeonov A, Huang R. Xu T, et al. Among authors: sakamuru s. J Chem Inf Model. 2023 Feb 13;63(3):846-855. doi: 10.1021/acs.jcim.2c01516. Epub 2023 Jan 31. J Chem Inf Model. 2023. PMID: 36719788 Free PMC article.

4

Screening Method for the Identification of Compounds That Activate Pregnane X Receptor.

Lynch C, Sakamuru S, Xia M. Lynch C, et al. Among authors: sakamuru s. Curr Protoc. 2022 Dec;2(12):e615. doi: 10.1002/cpz1.615. Curr Protoc. 2022. PMID: 36469580 Free PMC article.

5

Prediction of drug-induced liver injury and cardiotoxicity using chemical structure and in vitro assay data.

Ye L, Ngan DK, Xu T, Liu Z, Zhao J, Sakamuru S, Zhang L, Zhao T, Xia M, Simeonov A, Huang R. Ye L, et al. Among authors: sakamuru s. Toxicol Appl Pharmacol. 2022 Nov 1;454:116250. doi: 10.1016/j.taap.2022.116250. Epub 2022 Sep 20. Toxicol Appl Pharmacol. 2022. PMID: 36150479 Free PMC article.

6

Use of Tox21 Screening Data to Evaluate the COVID-19 Drug Candidates for Their Potential Toxic Effects and Related Pathways.

Sakamuru S, Huang R, Xia M. Sakamuru S, et al. Front Pharmacol. 2022 Jul 14;13:935399. doi: 10.3389/fphar.2022.935399. eCollection 2022. Front Pharmacol. 2022. PMID: 35910344 Free PMC article. Review.

7

Identification of Selective CYP3A7 and CYP3A4 Substrates and Inhibitors Using a High-Throughput Screening Platform.

Kabir M, Padilha EC, Shah P, Huang R, Sakamuru S, Gonzalez E, Ye L, Hu X, Henderson MJ, Xia M, Xu X. Kabir M, et al. Among authors: sakamuru s. Front Pharmacol. 2022 Jul 1;13:899536. doi: 10.3389/fphar.2022.899536. eCollection 2022. Front Pharmacol. 2022. PMID: 35847040 Free PMC article.

8

Improving the solubility and antileukemia activity of Wnt/β-catenin signaling inhibitors by disrupting molecular planarity.

Ai Y, Sakamuru S, Imler G, Xia M, Xue F. Ai Y, et al. Among authors: sakamuru s. Bioorg Med Chem. 2022 Sep 1;69:116890. doi: 10.1016/j.bmc.2022.116890. Epub 2022 Jun 20. Bioorg Med Chem. 2022. PMID: 35777269 Free PMC article.

9

Targeting CAR and Nrf2 improves cyclophosphamide bioactivation while reducing doxorubicin-induced cardiotoxicity in triple-negative breast cancer treatment.

Stern S, Liang D, Li L, Kurian R, Lynch C, Sakamuru S, Heyward S, Zhang J, Kareem KA, Chun YW, Huang R, Xia M, Hong CC, Xue F, Wang H. Stern S, et al. Among authors: sakamuru s. JCI Insight. 2022 Jun 22;7(12):e153868. doi: 10.1172/jci.insight.153868. JCI Insight. 2022. PMID: 35579950 Free PMC article.

10

Mitochondrial Membrane Potential Assay.

Sakamuru S, Zhao J, Attene-Ramos MS, Xia M. Sakamuru S, et al. Methods Mol Biol. 2022;2474:11-19. doi: 10.1007/978-1-0716-2213-1_2. Methods Mol Biol. 2022. PMID: 35294751 Free PMC article.

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