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Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics.
Bosc E, Anastasie J, Soualmia F, Coric P, Kim JY, Wang LQ, Lacin G, Zhao K, Patel R, Duplus E, Tixador P, Sproul AA, Brugg B, Reboud-Ravaux M, Troy CM, Shelanski ML, Bouaziz S, Karin M, El Amri C, Jacotot ED. Bosc E, et al. Among authors: sproul aa. Cell Death Dis. 2022 Nov 15;13(11):959. doi: 10.1038/s41419-022-05396-2. Cell Death Dis. 2022. PMID: 36379916 Free PMC article.
Genetic control of manno(fructo)kinase activity in Escherichia coli.
Sproul AA, Lambourne LT, Jean-Jacques D J, Kornberg HL. Sproul AA, et al. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15257-9. doi: 10.1073/pnas.211569798. Epub 2001 Dec 11. Proc Natl Acad Sci U S A. 2001. PMID: 11742072 Free PMC article.
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons.
Al-Dalahmah O, Lam M, McInvale JJ, Qu W, Nguyen T, Mun JY, Kwon S, Ifediora N, Mahajan A, Humala N, Winters T, Angeles E, Jakubiak KA, Kühn R, Kim YA, De Rosa MC, Doege CA, Paryani F, Flowers X, Dovas A, Mela A, Lu H, DeTure MA, Vonsattel JP, Wszolek ZK, Dickson DW, Kuhlmann T, Zaehres H, Schöler HR, Sproul AA, Siegelin MD, De Jager PL, Goldman JE, Menon V, Canoll P, Hargus G. Al-Dalahmah O, et al. Among authors: sproul aa. Cell Stem Cell. 2024 May 2;31(5):676-693.e10. doi: 10.1016/j.stem.2024.03.013. Epub 2024 Apr 15. Cell Stem Cell. 2024. PMID: 38626772 Free article.
CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage.
Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, McLean PJ, Sproul AA, Saha K, Roy S. Sun J, et al. Among authors: sproul aa. Nat Commun. 2019 Jan 3;10(1):53. doi: 10.1038/s41467-018-07971-8. Nat Commun. 2019. PMID: 30604771 Free PMC article.
29 results