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86 results

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Identifying weak signals to prepare for uncertainty in the energy sector.
Gilmore N, Koskinen I, Burr P, Obbard E, Sproul A, Konstantinou G, Bilbao J, Daiyan R, Kay M, Corkish R, Macgill I, Lovell E, Menictas C, Bruce A. Gilmore N, et al. Among authors: sproul a. Heliyon. 2023 Oct 20;9(11):e21295. doi: 10.1016/j.heliyon.2023.e21295. eCollection 2023 Nov. Heliyon. 2023. PMID: 37920500 Free PMC article.
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons.
Al-Dalahmah O, Lam M, McInvale JJ, Qu W, Nguyen T, Mun JY, Kwon S, Ifediora N, Mahajan A, Humala N, Winters T, Angeles E, Jakubiak KA, Kühn R, Kim YA, De Rosa MC, Doege CA, Paryani F, Flowers X, Dovas A, Mela A, Lu H, DeTure MA, Vonsattel JP, Wszolek ZK, Dickson DW, Kuhlmann T, Zaehres H, Schöler HR, Sproul AA, Siegelin MD, De Jager PL, Goldman JE, Menon V, Canoll P, Hargus G. Al-Dalahmah O, et al. Among authors: sproul aa. Cell Stem Cell. 2024 May 2;31(5):676-693.e10. doi: 10.1016/j.stem.2024.03.013. Epub 2024 Apr 15. Cell Stem Cell. 2024. PMID: 38626772 Free article.
A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease.
Haage V, Tuddenham JF, Comandante-Lou N, Bautista A, Monzel A, Chiu R, Fujita M, Garcia FG, Bhattarai P, Patel R, Buonfiglioli A, Idiarte J, Herman M, Rinderspacher A, Mela A, Zhao W, Argenziano MG, Furnari JL, Banu MA, Landry DW, Bruce JN, Canoll P, Zhang Y, Nuriel T, Kizil C, Sproul AA, de Witte LD, Sims PA, Menon V, Picard M, De Jager PL. Haage V, et al. Among authors: sproul aa. bioRxiv [Preprint]. 2024 Feb 6:2024.02.06.579103. doi: 10.1101/2024.02.06.579103. bioRxiv. 2024. PMID: 38370689 Free PMC article. Preprint.
ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's Disease.
Bartosch AMW, Youth EHH, Hansen S, Wu Y, Buchanan HM, Kaufman ME, Xiao H, Koo SY, Ashok A, Sivakumar S, Soni RK, Dumitrescu LC, Lam TG, Ropri AS, Lee AJ, Klein HU, Vardarajan BN, Bennett DA, Young-Pearse TL, De Jager PL, Hohman TJ, Sproul AA, Teich AF. Bartosch AMW, et al. Among authors: sproul aa. J Neurosci. 2024 Jan 17;44(3):e2324222023. doi: 10.1523/JNEUROSCI.2324-22.2023. J Neurosci. 2024. PMID: 38050142
ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease.
Bartosch AMW, Youth EHH, Hansen S, Kaufman ME, Xiao H, Koo SY, Ashok A, Sivakumar S, Soni RK, Dumitrescu LC, Lam TG, Ropri AS, Lee AJ, Klein HU, Vardarajan BN, Bennett DA, Young-Pearse TL, De Jager PL, Hohman TJ, Sproul AA, Teich AF. Bartosch AMW, et al. Among authors: sproul aa. bioRxiv [Preprint]. 2023 Mar 21:2023.03.21.533654. doi: 10.1101/2023.03.21.533654. bioRxiv. 2023. PMID: 36993746 Free PMC article. Updated. Preprint.
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics.
Bosc E, Anastasie J, Soualmia F, Coric P, Kim JY, Wang LQ, Lacin G, Zhao K, Patel R, Duplus E, Tixador P, Sproul AA, Brugg B, Reboud-Ravaux M, Troy CM, Shelanski ML, Bouaziz S, Karin M, El Amri C, Jacotot ED. Bosc E, et al. Among authors: sproul aa. Cell Death Dis. 2022 Nov 15;13(11):959. doi: 10.1038/s41419-022-05396-2. Cell Death Dis. 2022. PMID: 36379916 Free PMC article.
RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation.
Kim YA, Siddiqui T, Blaze J, Cosacak MI, Winters T, Kumar A, Tein E, Sproul AA, Teich AF, Bartolini F, Akbarian S, Kizil C, Hargus G, Santa-Maria I. Kim YA, et al. Among authors: sproul aa. Acta Neuropathol. 2023 Jan;145(1):29-48. doi: 10.1007/s00401-022-02511-7. Epub 2022 Nov 10. Acta Neuropathol. 2023. PMID: 36357715 Free PMC article.
86 results